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Harpreet Kaur

3 papers in the library · 17 citations · publishing 2023-2024

Papers

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Uncovering Structure-Activity Relationships of Phenethylamines: Paving the Way for Innovative Mental Health Treatments.

ACS Chemical Neuroscience February 21, 2024 Sedat Karabulut, Harpreet Kaur, James W Gauld

The rapidly evolving psychedelic industry has garnered considerable attention due to 3,4-methylenedioxymethamphetamine-assisted psychotherapy's ground-breaking success in treating moderate-to-severe Post-traumatic Stress Disorder in two Phase 3 clinical trials. This has opened Pandora's box for the development of innovative therapeutic modalities. Of particular interest are the phenethylamines...

Balancing Therapeutic Efficacy and Safety of MDMA and Novel MDXX Analogues as Novel Treatments for Autism Spectrum Disorder.

Psychedelic Medicine September 1, 2023 Harpreet Kaur, Sedat Karabulut, James W Gauld et al. 10 citations

Autism spectrum disorder (ASD) encompasses a range of neurodevelopmental syndromes diagnostically characterized by deficits in social communication and social interaction and repetitive, inflexible patterns of behaviors, interests, and thoughts. ASD affects people worldwide, irrespective of race, ethnicity, or socio-economic status, with debilitating effects on employment and interpersonal...

Applications and Potential of In Silico Approaches for Psychedelic Chemistry

Molecules August 9, 2023 Sedat Karabulut, Harpreet Kaur, James W Gauld 7 citations

Molecular-level investigations of the Central Nervous System have been revolutionized by the development of computational methods, computing power, and capacity advances. These techniques have enabled researchers to analyze large amounts of data from various sources, including genomics, in vivo, and in vitro drug tests. In this review, we explore how computational methods and informatics have...