medRxiv
August 31, 2026
Jonathan Huntley, Benjy Barnett, Daniel Bor et al.
preprint
Despite extensive knowledge of the progressive sequence of cognitive and functional deficits in Alzheimer's Disease (AD), the impact of neurodegeneration on the conscious experience of patients remains largely unexplored. Understanding how the content of consciousness, particularly perceptual awareness, changes with the progression of AD is crucial to enable meaningful person-centred care. This...
Current Neurology and Neuroscience Reports
August 1, 2024
Daniel C Mograbi, Rafael S. Rodrigues, Bheatrix Bienemann et al.
12 citations
Self-awareness can be defined as the capacity of becoming the object of one's own awareness and, increasingly, it has been the target of scientific inquiry. Self-awareness has important clinical implications, and a better understanding of the neurochemical basis of self-awareness may help clarifying causes and developing interventions for different psychopathological conditions. The current...
Wiley Interdisciplinary Reviews Cognitive Science
December 3, 2023
Daniel C Mograbi, Simon Hall, Beatriz Arantes et al.
17 citations
Abstract Self‐awareness, the ability to take oneself as the object of awareness, has been an enigma for our species, with different answers to this question being provided by religion, philosophy, and, more recently, science. The current review aims to discuss the neurocognitive mechanisms underlying self‐awareness. The multidimensional nature of self‐awareness will be explored, suggesting how...
Alzheimer's & dementia (New York, N. Y.)
2021
Jonathan Huntley, Stephen M Fleming, Daniel C Mograbi et al.
People with Alzheimer's disease (AD) demonstrate a range of alterations in consciousness. Changes in awareness of cognitive deficit, self-awareness, and introspection are seen early in AD, and dysfunction of awareness and arousal progresses with increasing disease severity. However, heterogeneity of deficits between individuals and a lack of empirical studies in people with severe dementia...