npj Biological Timing and Sleep
June 22, 2026
I. Papp, Zoran Cvetković, Nazanin Biabani et al.
Abstract Nightmare disorder is historically conceptualised as a rapid eye movement (REM) sleep parasomnia, but evidence also points to altered non-rapid eye movement (NREM) sleep physiology. Here, in a retrospective case-control study, we analysed overnight polysomnography from 26 adults with nightmare disorder and 32 controls using a harmonised event-based EEG pipeline. Nightmare disorder...
Frontiers in Sleep
September 11, 2025
Nazanin Biabani, Martina Mulas, Carlotta Mutti et al.
2 citations
Background: REM sleep behavior disorder (RBD) is characterized by loss of normal muscle atonia during REM sleep, often associated with dream enactment behaviors, and is typically a prodromal neurodegenerative condition in middle-aged and older adults. However, emerging case reports and case series suggest that not all RBD presentations follow this trajectory, particularly in younger...
Journal of Sleep Research
June 1, 2025
Liborio Parrino, Francesco Rausa, Giulia Balella et al.
4 citations
This article aims at providing a comprehensive review of the historical discovery and following research on rapid eye movement (REM) sleep, highlighting its manifold nature as a behavioural, electrophysiological and dreaming state. Pioneering works conducted by Aserinsky, Kleitman, Dement and Jouvet established the foundational understanding of REM sleep recurrence, brainstem mechanisms, and...
Journal of Sleep Research
October 3, 2024
Carlotta Mutti, Francesca Siclari, Ivana Rosenzweig
2 citations
Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the discovery of rapid eye movement (REM) sleep in the 1950s....
Nature and Science of Sleep
March 1, 2024
Qi Rui See, Kausar Raheel, Iain Duncan et al.
8 citations
Background: Speech graph analysis (SGA) of dreams has recently shown promise as an objective and language-invariant diagnostic tool that can aid neuropsychiatric diagnosis. Whilst the notion that dreaming mentations reflect distinct physiologic processes is not new, such studies in patients with sleep disorders remain exceptionally scarce. Here, using SGA and other dream content analyses, we...
Croatian Medical Journal
December 1, 2022
Omolade Longe, A. Omodan, Guy Leschziner et al.
8 citations
AIM: To establish patterns or themes of dreams and dreamlike mentation content reported in all forms of non-rapid eye movement (NREM) parasomnias and to identify gaps in the current understanding of this topic. METHODS: A scoping review of available evidence on dreams and dreamlike mentation in NREM parasomnias was conducted in accordance with the PRISMA-ScR guidelines. We searched...
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
June 15, 2020
Valentina Gnoni, Sean Higgins, Alexander David Nesbitt et al.
12 citations
Unpleasant dreamlike mentation can occur during non-rapid eye movement parasomnias, leading to associated panic attacks. The mentations are rarely remembered and are likely underreported. However, they may lead to significant personal distress and, if not addressed, may contribute to poorer clinical outcomes. Cotard le délire de negation are very rare nihilistic delusions, historically...
Neuroscience and Biobehavioral Reviews
May 1, 2013
Zoran Vukadinovic, Merrill S Herman, Ivana Rosenzweig
The role of cannabis in the etiology of schizophrenia has been documented as possibly the strongest environmental risk factor. However, the pathomechanism whereby cannabis use increases this risk has not yet been identified. We argue that this pathomechanism may involve direct effects of exogenous cannabinoids on T-type calcium channels in the thalamus. These channels are crucial for...