Journal of Psychiatric Research
June 1, 2026
Amanda W Baker, Samantha R Philip, Caroline H Armstrong et al.
Self-compassion is recognized as important for psychological well-being and has been linked to reduced anxiety levels. Mindfulness-based interventions, such as the 8-week Mindfulness-Based Stress Reduction program (MBSR), have shown promise in treating anxiety disorders, but no studies to date have compared the effects of MBSR to the gold-standard medication treatment (escitalopram) on...
Journal of Affective Disorders
September 1, 2025
Elizabeth A Hoge, Mihriye Mete, Amanda W Baker et al.
3 citations
During the pandemic, a randomized controlled trial (RCT) of Mindfulness-Based Stress Reduction (MBSR) versus the antidepressant, escitalopram (ESC) added a second phase using a synchronous, videoconference (VC) format for both interventions, enabling randomized and naturalistic comparisons. The original in-person RCT demonstrated non-inferiority of MBSR to ESC. In the second phase, we...
JAMA Network Open
October 1, 2024
Hiroe Hu, Mihriye Mete, Neil K Rustgi et al.
This secondary analysis of a randomized clinical trial assesses patient-reported anxiety, depression, and quality of life among patients receiving mindfulness-based stress reduction vs escitalopram for the treatment of anxiety disorders.
Journal of Mood and Anxiety Disorders
June 1, 2024
Danielle Moskow Diamond, David Rosenfield, Nikki Kaiser et al.
5 citations
Improving mindfulness is an important treatment target for generalized anxiety disorder (GAD). However, less is known about how different treatments impact specific aspects of mindfulness. In a clinical trial (Simon et al., 2021), 226 individuals with GAD were randomized to 12 weeks of Kundalini Yoga (KY), cognitive behavioral therapy (CBT) or stress education (SE). To examine whether specific...
JAMA Psychiatry
January 1, 2023
Elizabeth A Hoge, Eric Bui, Mihriye Mete et al.
Anxiety disorders are common, highly distressing, and impairing conditions. Effective treatments exist, but many patients do not access or respond to them. Mindfulness-based interventions, such as mindfulness-based stress reduction (MBSR) are popular and can decrease anxiety, but it is unknown how they compare to standard first-line treatments. To determine whether MBSR is noninferior to...
Irish Journal of Psychological Medicine
August 19, 2020
John R. Kelly, Matthew Crockett, Laith Alexander et al.
16 citations
The medium- to long-term consequences of COVID-19 are not yet known, though an increase in mental health problems are predicted. Multidisciplinary strategies across socio-economic and psychological levels may be needed to mitigate the mental health burden of COVID-19. Preliminary evidence from the rapidly progressing field of psychedelic science shows that psilocybin therapy offers a promising...