Quarterly Journal of Experimental Psychology
September 1, 2024
Jordan J Wehrman, Clara C Chung, Robert D. Sanders
Consciousness requires subjective experience in the "now." Establishing "now," however, necessitates temporal processing. In the current article, we review one method of altering consciousness, anaesthetic drug administration, and its effects on perceived duration. We searched PubMed, PsycInfo, and ScienceDirect databases, and article reference sections, for combinations of anaesthetic drugs...
British Journal of Anaesthesia
October 2023
Jordan J Wehrman, Cameron P Casey, Sean Tanabe et al.
Sensory disconnection is a key feature of sleep and anaesthesia. We have proposed that predictive coding offers a framework for understanding the mechanisms of disconnection. Low doses of ketamine that do not induce disconnection should thus diminish predictive coding, but not abolish it. Ketamine was administered to 14 participants up to a blood concentration of 0.3 μg ml-1 Participants were...
British Journal of Anaesthesia
October 1, 2023
Andrew J F Turner, Jordan J Wehrman, Robert D. Sanders
The subjective experiences of sedation or anaesthesia are underexplored. A recent study by Valli and colleagues (Br J Anaesth 2023; 131: 348-59) found similar frequency and content of recalled experiences after both non-rapid eye movement sleep and target-controlled infusions of propofol or dexmedetomidine titrated to verbal unresponsiveness. The authors find that the phenomenological...
James Thurbon, Annabelle Mitchell, Jordan J Wehrman et al.
preprint
Flicker light stimulation shows promise for inducing visual imagery, altered states of consciousness, and changes in arousal, with potential applications in relaxation and imagery-based therapeutic interventions. However, optimal utility depends on identifying how viewing conditions shape subjective and physiological outcomes. We examined whether eye condition (open, closed) modulates...