Effects of chronic ibogaine treatment on cerebellar Purkinje cells in the rat.
Brain Research June 13, 1997 Scott Helsley, C A Dlugos, R J Pentney et al. 19 citations
The present investigation assessed the chronic toxicity of ibogaine on cerebellar Purkinje cells in male Fischer 344 rats. A behaviorally active dose of ibogaine (10 mg/kg, i.p.) was administered to a group of six subjects every other day for 60 days while the control group received an equivalent volume of saline (1 ml/kg). Estimates of Purkinje cell number were determined using the optical...