Anxiety-like behavior induced by salicylate depends on age and can be prevented by a single dose of 5-MeO-DMT.
Experimental Neurology April 1, 2020 Jessica Winne, Barbara C Boerner, Thawann Malfatti et al. 34 citations
Salicylate intoxication is a cause of tinnitus and comorbidly associated with anxiety in humans. In a previous work, we showed that salicylate induces anxiety-like behavior and hippocampal type 2 theta oscillations (theta2) in mice. Here we investigate if the anxiogenic effect of salicylate is dependent on age and previous tinnitus experience. We also tested whether a single dose of DMT can...