Taylor A Flatt

From molecules to meaning: unpacking the antidepressant mechanisms of psychedelic drugs.

Expert Review of Clinical Pharmacology June 11, 2025 Victor Pablo Acero, Taylor A Flatt, Peter M. Gooch et al.

Psychedelic compounds are emerging treatments for depression, capable of producing rapid and lasting symptom reduction after 1-2 administrations in the context of psychotherapy - a stark contrast to traditional antidepressants. Despite promising outcomes, the mechanisms underlying psychedelics' reported antidepressant effects remain poorly understood and are often framed in fragmented ways....