Adding facilitator-supported mindfulness-based self-help (MBSH) to usual treatment leads to faster and greater reductions in anxiety and depression for people with emotional disorders. In a randomized trial with 302 patients from four centers, those who received MBSH plus usual care showed significantly more improvement in symptoms, mindfulness, physical symptoms, stress, sleep, and inner peace immediately after the program compared to those receiving usual care alone. Some benefits, including reduced depression and stress and increased mindfulness, appeared as early as three to five weeks and were maintained three months later. The approach is a scalable and effective addition to clinical practice.
A 49-day online mindfulness intervention for emotional distress (MIED) increased attentional control and reduced anxiety and depression in 498 adults with high emotional distress, compared with a waitlist control group. Changes became evident by the third week. Statistical analyses showed that improvements in attentional control mediated the program's effects on later anxiety and depression levels. The findings suggest that mindfulness-based programs may alleviate emotional distress partly by strengthening attentional control.
Two randomized controlled trials tested whether cognitive flexibility—the ability to shift attention—explains how a mindfulness intervention reduces emotional distress. In Study 1, 607 highly distressed adults were assigned to an eight-week mindfulness program or a waitlist. In Study 2, 89 similar participants were assigned to the program or a control group. Both trials showed that the mindfulness program significantly improved anxiety, depression, and general distress. Changes in cognitive flexibility during the intervention statistically mediated later reductions in emotional distress. Specifically, shifting attention away from affective to nonaffective aspects of positive stimuli at week 5, and less shifting from negative to positive affective aspects at week 3, predicted greater distress relief at week 7. The findings indicate cognitive flexibility is a key mechanism of mindfulness-based intervention for emotional distress.
A meta-analysis of 10 randomized controlled trials involving 1,058 people with insomnia and anxiety-depressive symptoms found that adding 4–12 weeks of mindfulness therapy to conventional treatment significantly reduced depression and anxiety scores compared with conventional treatment alone. Mindfulness therapy lowered Hamilton Depression Scale scores by an average of 3.67 points and Hamilton Anxiety Scale scores by 3.23 points. It also reduced Self-Rating Depression Scale scores by 6.49 points and Self-Rating Anxiety Scale scores by 7.97 points. The authors conclude that mindfulness therapy can improve anxiety and depression symptoms in people with insomnia, though they note methodological limitations and call for further well-designed trials.