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Cristian Coarfa

2 papers in the library · 11 citations · publishing 2025-2026

Papers

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C29-12 Psilocybin Treatment Could Improve Outcomes for Age-associated Lung Diseases

American Journal of Respiratory and Critical Care Medicine May 1, 2026 L. Hecker, J. Kleinhenz, C. Coarfa et al.

The elderly population is rapidly growing. Overwhelming epidemiologic data has demonstrated worse health outcomes with increasing age for a multitude of lung diseases (COVID being one of numerous examples). There is an increasingly urgent need for a more complete understanding of the molecular pathways and biological processes underlying aging to improve outcomes for age-associated lung...

Psilocybin treatment extends cellular lifespan and improves survival of aged mice

npj Aging July 8, 2025 Kosuke Kato, Yoon-Joo Shin, Cristian Coarfa et al. 11 citations

Abstract Psilocybin, the naturally occurring psychedelic compound produced by hallucinogenic mushrooms, has received attention due to considerable clinical evidence for its therapeutic potential to treat various psychiatric and neurodegenerative indications. However, the underlying molecular mechanisms remain enigmatic, and few studies have explored its systemic impacts. We provide the first...