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Ignacio Perez-Ipina

4 papers in the library · 163 citations · publishing 2020-2021

Papers

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Nonequilibrium brain dynamics as a signature of consciousness

Physical review. E July 28, 2021 Yonatan Sanz Perl, Hernan Bocaccio, Carla Pallavicini et al. 82 citations

The cognitive functions of human and nonhuman primates rely on the dynamic interplay of distributed neural assemblies. As such, it seems unlikely that cognition can be supported by macroscopic brain dynamics at the proximity of equilibrium. We confirmed this hypothesis by investigating electrocorticography data from nonhuman primates undergoing different states of unconsciousness (sleep, and...

Non-equilibrium brain dynamics as a signature of consciousness

arXiv Preprint Archive December 19, 2020 Yonatan Sanz Perl, Hernan Bocaccio, Ignacio Perez-Ipina et al.

The cognitive functions of human and non-human primates rely on the dynamic interplay of distributed neural assemblies. As such, it seems unlikely that cognition can be supported by macroscopic brain dynamics at the proximity of thermodynamic equilibrium. We confirmed this hypothesis by investigating electrocorticography data from non human primates undergoing different states of...

Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness

bioRxiv Preprint Server July 2, 2020 Yonatan Sanz Perl, Carla Pallavicini, Ignacio Perez-Ipina et al. preprint

Consciousness transiently fades away during deep sleep, more stably under anesthesia, and sometimes permanently due to brain injury. The development of an index to quantify the level of consciousness across these different states is regarded as a key problem both in basic and clinical neuroscience. We argue that this problem is ill-defined since such an index would not exhaust all the relevant...

Modeling regional changes in dynamic stability during sleep and wakefulness

Neuroimage April 11, 2020 Ignacio Perez-Ipina, Patricio Donnelly Kehoe, Morten L. Kringelbach et al. 81 citations

Global brain states are frequently placed within a unidimensional continuum by correlational studies, ranging from states of deep unconsciousness to ordinary wakefulness. An alternative is their multidimensional and mechanistic characterization in terms of different cognitive capacities, using computational models to reproduce the underlying neural dynamics. We explore this alternative by...