Ketamine has been widely used since its discovery, and in addition to its anesthetic effects, in recent years it has been found to exhibit rapid and sustained antidepressant effects in rodent models and in patients with treatment-resistant depression (TRD) at subanesthetic doses. The antidepressant mechanism of ketamine has also been intensively studied, involving glutamate receptors such as...
Meditation has gained increasing recognition as a simple, cost-effective, and non-invasive therapeutic approach for older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's disease (AD). This meta-analysis aimed to systematically evaluate its effectiveness on this population. A comprehensive search across nine databases was performed from inception...
With a wealth of scientifically proven health benefits, meditation was enjoyed by about 18 million people in the U.S. alone, as of 2012. Yet, there remains a stunning lack of convenient tools for promoting long-term and effective meditation practice. In this paper, we present MindfulWatch, a practical smartwatch-based sensing system that monitors respiration in real-time during meditation --...