Ketamine has been widely used since its discovery, and in addition to its anesthetic effects, in recent years it has been found to exhibit rapid and sustained antidepressant effects in rodent models and in patients with treatment-resistant depression (TRD) at subanesthetic doses. The antidepressant mechanism of ketamine has also been intensively studied, involving glutamate receptors such as...
Meditation has gained increasing recognition as a simple, cost-effective, and non-invasive therapeutic approach for older adults with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's disease (AD). This meta-analysis aimed to systematically evaluate its effectiveness on this population. A comprehensive search across nine databases was performed from inception...