Unique Effects of (R)-Ketamine Compared to (S)-Ketamine on EEG Theta Power in Rats.
Pharmaceuticals (Basel, Switzerland) February 1, 2024 Dóra Pothorszki, Szabolcs Koncz, Dóra Török et al. 7 citations
Differences in the pharmacological effects of (S)-ketamine and (R)-ketamine are at the focus of research. Clinical data and our rat studies confirmed the antidepressant effect of (S)- but not (R)-ketamine, with similar differences in quantitative electroencephalogram (EEG) and sleep effects. In contrast, studies mainly on mice showed some stronger, preferable effects of (R)-ketamine. EEG theta...