Differential effects of ketamine enantiomers on EEG parameters including the gamma-delta shift phenomenon.
British Journal of Pharmacology June 1, 2026 Szabolcs Koncz, Dóra Pothorszki, Noémi Papp et al. 2 citations
Ketamine consists of two enantiomers, (R)-ketamine and (S)-ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)-enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)-ketamine. The quantitative electroencephalography (qEEG) gamma-enhancing effect of...
DOI: 10.1111/bph.70399 (opens in new tab)
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Arketamine
Esketamine
Arousal
Biomarker
+3