Jeremy A Ebert

2 papers in the library · publishing 2011-2016

Papers

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Potentiation of Ecstasy-induced hyperthermia and FAT/CD36 expression in chronically exercised animals.

Temperature March 30, 2016 Sandra L Hrometz, Jeremy A Ebert, Karen E Grice et al.

Fatal hyperthermia as a result of 3,4-methylenedioxymethamphetamine (MDMA) use involves non-esterified free fatty acids (NEFA) and the activation of mitochondrial uncoupling proteins (UCP). NEFA gain access into skeletal muscle via specific transport proteins, including fatty acid translocase (FAT/CD36). FAT/CD36 expression is known to increase following chronic exercise. Previous studies have...

DOI: 10.1080/23328940.2016.1166310 Full text MDMA Hyperthermia Fat/cd36 Chronic exercise +1

Identification of a possible role for atrial natriuretic peptide in MDMA-induced hyperthermia.

Toxicology Letters October 10, 2011 Sandra L Hrometz, Karen Thatcher, Jeremy A Ebert et al.

MDMA (3,4-methylenedioxymethamphetamine) induces thermogenesis in a mitochondrial uncoupling protein 3-dependent manner. There is evidence that this hyperthermia is mediated in part by the lipolytic release of free fatty acids, that subsequently activate uncoupling protein 3 in skeletal muscle mitochondria. We hypothesize that atrial natriuretic peptide (ANP), a strong lipolytic mediator, may...

DOI: 10.1016/j.toxlet.2011.07.025 Full text