Noah A. Omeiza

2 papers in the library · 6 citations · publishing 2022-2025

Papers

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Inhibition of oxidative stress, neuroinflammatory cytokines, and protein expressions contributes to the antipsychotic effects of geraniol in mice with ketamine-induced schizophrenia.

Journal of Neuroimmune Pharmacology July 3, 2025 Christian I Uruaka, Benneth Ben-Azu, Noah A. Omeiza et al. 6 citations

Imbalances in redox and neuroinflammation are believed to play a role in the complex causes of schizophrenia, a widespread mental disorder characterized by abnormal behaviour. In this regard, we investigated the effects of geraniol, a natural compound with various medicinal uses, on ketamine-induced schizophrenia-like behaviour, oxidative stress and neuroinflammation in mice. We conducted three...

DOI: 10.1007/s11481-025-10226-1 Full text Anti-inflammation Antioxidant Geraniol Neuroinflammation +1

Mechanisms underpinning Carpolobia lutea G. Don ethanol extract's neurorestorative and antipsychotic-like activities in an NMDA receptor antagonist model of schizophrenia.

Journal of Ethnopharmacology October 1, 2022 Noah A. Omeiza, A. Bakre, Benneth Ben-Azu et al.

ETHNOPHARMACOLOGICAL RELEVANCE Persistent ketamine insults to the central nervous system block NMDA receptors and disrupt putative neurotransmission, oxido-nitrosative, and inflammatory pathways, resulting in schizophrenia-like symptoms in animals. Previously, the ethnomedicinal benefits of Carpolobia lutea against insomnia, migraine headache, and insanity has been documented, but the...

DOI: 10.1016/j.jep.2022.115767