Inhibition of oxidative stress, neuroinflammatory cytokines, and protein expressions contributes to the antipsychotic effects of geraniol in mice with ketamine-induced schizophrenia.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology July 3, 2025 Christian I Uruaka, Benneth Ben-Azu, Noah A Omeiza et al. 6 citations
Imbalances in redox and neuroinflammation are believed to play a role in the complex causes of schizophrenia, a widespread mental disorder characterized by abnormal behaviour. In this regard, we investigated the effects of geraniol, a natural compound with various medicinal uses, on ketamine-induced schizophrenia-like behaviour, oxidative stress and neuroinflammation in mice. We conducted three...