Functional changes in sleep-related arousal after ketamine administration in individuals with treatment-resistant depression.
Translational Psychiatry June 4, 2024 Elizabeth D. Ballard, Deanna K Greenstein, Philip T Reiss et al. 16 citations
The glutamatergic modulator ketamine is associated with changes in sleep, depression, and suicidal ideation (SI). This study sought to evaluate differences in arousal-related sleep metrics between 36 individuals with treatment-resistant major depression (TRD) and 25 healthy volunteers (HVs). It also sought to determine whether ketamine normalizes arousal in individuals with TRD and whether...