Transnasal ventral brainstem stimulation reverses anesthesia-induced unconsciousness in sheep.
Brain Stimulation March 6, 2026 Jingyu Feng, Bin Liu, Zhijun Zhao et al.
Background: Brainstem reticular formation (BRF) is crucially involved in regulating arousal, making it a potential target for reversing general anesthesia. The transnasal approach provides a minimally invasive access to the ventral brainstem. However, whether this approach can effectively modulate arousal remains unknown. Objective: To evaluate the efficacy of transnasal BRF electrical...
DOI: 10.1016/j.brs.2026.103068 (opens in new tab)
Brain stem
Reticular formation
Animals
Sheep
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