Alba Cáceres-Rodríguez

2 papers in the library · publishing 2026

Papers

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Prenatal Cannabidiol and Δ9-Tetrahydrocannabinol exposure lead to sex-specific disruptions in risk assessment and behavioral switching via divergent rewiring of the adult mPFC

bioRxiv July 2, 2026 Alba Cáceres-Rodríguez, Daniela Iezzi, Olivier Lassalle et al. preprint

Background Prenatal cannabidiol (CBD) consumption is increasing, driven by a perception of safety relative to Δ9-tetrahydrocannabinol (THC). However, the neurodevelopmental risks of gestational CBD remain largely uncharacterized. Methods Using a sex-disaggregated framework, we investigated adult (P100–140) mouse offspring following in utero exposure (GD5-18; 3 mg/kg) to THC or CBD. Behavioral...

DOI: 10.64898/2026.06.27.734813 Full text

Prenatal Cannabidiol and THC Exposure Induce Sex-Specific Executive Dysfunction via Divergent Pathological Rewiring of the Adult Medial Prefrontal Cortex

Olivier J. J. Manzoni, Alba Cáceres-Rodríguez, Daniela Iezzi et al. preprint

Abstract Prenatal cannabidiol (CBD) consumption is rapidly increasing, driven by a perception of safety relative to delta9-tetrahydrocannabinol (THC). However, the long-term neurodevelopmental risks of gestational CBD remain largely uncharacterized. Using a sex-disaggregated framework, we investigated adult (P100–140) mouse offspring following in utero exposure (GD5–18; 3 mg/kg) to THC or CBD....

DOI: 10.21203/rs.3.rs-9428628/v1