Mauro Federici

2 papers in the library · publishing 2007-2018

Papers

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3,4-Methylenedioxymethamphetamine (MDMA) Alters Synaptic Dopamine Release in the Dorsal Striatum Through Nicotinic Receptors and DAT Inhibition.

Neuroscience May 1, 2018 Francesca Romana Rizzo, Mauro Federici, Nicola Biagio Mercuri

An increase of extracellular dopamine (DA) has been implicated in the psychostimulant properties of 3,4-methylenedioxymethamphetamine (MDMA). Although this drug has been reported to affect the DA uptake transporter (DAT), it might activate other mechanisms to regulate the outflow of DA in the brain. Our aim was to examine the overall effects of MDMA on the release of DA in the striatum. We...

DOI: 10.1016/j.neuroscience.2018.02.037 Full text 3,4-Methylenedioxymethamphetamine MDMA Da transporter Cocaine Dopamine +1

Electrophysiologic changes in ventral midbrain dopaminergic neurons resulting from (+/-) -3,4-methylenedioxymethamphetamine (MDMA-"Ecstasy").

Biological Psychiatry September 15, 2007 Mauro Federici, Luca Sebastianelli, Silvia Natoli et al.

Although dopamine (DA) has been implicated in the psychostimulant properties of 3,4-methylenedioxymethamphetamine (MDMA), there is no detailed information on its modalities of action on single ventral midbrain dopaminergic neurons. We examined the actions of MDMA on intracellularly recorded dopaminergic neurons maintained in slices. At 1 micromol/L, MDMA depolarized and excited the cells; at 3...

DOI: 10.1016/j.biopsych.2006.11.019 Full text