Psilocybin lengthens hippocampal sharp wave ripples
bioRxiv August 20, 2026 Ilknur Kayikcioglu Bozkir, Ryan Lashin, Tiecheng Liu et al. preprint
Psilocybin is a psychedelic which has been shown to induce neural plasticity through activation of intracellular serotonergic 5-HT2A receptors. It also produces brain-wide changes in structural and functional connectivity and holds promise as a therapeutic compound for treating anxiety and depression. Despite links between psilocybin-induced plasticity, the psychedelic experience, and reduction...