Relative effectiveness of antidepressant treatments in treatment-resistant depression: a systematic review and network meta-analysis of randomized controlled trials.
Neuropsychopharmacology May 1, 2025 Johan Saelens, Anna Gramser, Victoria Watzal et al. 47 citations
This systematic review and network meta-analysis (NMA) sought to compare different antidepressant treatments for treatment-resistant depression (TRD) in order to facilitate evidence-based choices. A literature search of PubMed, Cochrane Library, and Embase from inception until April 13th, 2023 identified randomized, controlled trials (RCTs) of adults with depression who had not responded to at...
DOI: 10.1038/s41386-024-02044-5 (opens in new tab)
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Treatment-resistant depression
Depression treatment
Electroconvulsive therapy
Mental health interventions
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