Efficacy and safety of eight enhanced therapies for treatment-resistant depression: A systematic review and network meta-analysis of RCTs.
Psychiatry Research September 1, 2024 Qinghua Guo, Libo Guo, Yong Wang et al. 19 citations
Treatment-Resistant Depression (TRD) challenges psychiatric treatment, with existing guidelines covering only a subset of augmentation strategies. A network meta-analysis following PRISMA guidelines examined the efficacy and safety of TRD treatments, analyzing 72 randomized controlled trials from eight databases, assessing response and remission rates, tolerability, and safety through the...
DOI: 10.1016/j.psychres.2024.116018 (opens in new tab)
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Enhanced innovative therapies
Network meta-analysis
Treatment-resistant depression trd
Refractory depression
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