Adolescents experience extensive neurocognitive development, with cannabis use potentially impacting developmental trajectories. Here, we comprehensively assess the influence of adolescent cannabis use onset on neurocognitive trajectories and consider how recent delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) may influence neurocognition. We use the large, diverse longitudinal...
Chronic cannabis use (CU) can result in subtle deficits in cognitive performance that may be linked with alterations in underlying neural functioning. However, these network alterations are not well-characterized following monitored abstinence. Here, we evaluate differences in functional brain network activity associated with CU patterns in adolescents/young adults. Functional connectomes were...
Background. Numerous neuropsychological studies have shown that cannabis use during adolescence and young adulthood led to deficits in sustained and selective attention. However, few studies have examined functional connectivity in attentional networks among young cannabis users, nor have characterized relationships with cannabis use patterns following abstinence. Methods. Differences in...
Highlights • We examined resting state connectivity in the DMN in cannabis users and controls.• Cannabis users displayed abnormal connectivity compared to healthy controls.• Abnormal connectivity in cannabis users related to poorer cognitive performance.• Abnormal brain communication may remain after ≥ 3 weeks of cannabis abstinence.