Handan Gunduz-Bruce

2 papers in the library · 7 citations · publishing 2012-2025

Papers

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Gamma Oscillations and Excitation/Inhibition Imbalance: Parallel Effects of NMDA Receptor Antagonism and Psychosis.

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging January 18, 2025 Brian J Roach, Judith M. Ford, Spero Nicholas et al. 7 citations

Auditory steady-state response (ASSR) abnormalities in the 40-Hz (gamma band) frequency have been observed in schizophrenia and in rodent studies of NMDA receptor (NMDAR) hypofunction. However, the extent to which 40-Hz ASSR abnormalities in schizophrenia resemble deficits in 40-Hz ASSR induced by acute administration of ketamine, an NMDAR antagonist, is not yet known. To address this knowledge...

DOI: 10.1016/j.bpsc.2025.01.008 Full text Ketamine Electroencephalography EEG Nmda receptor nmdar Schizophrenia +4

Glutamatergic modulation of auditory information processing in the human brain.

Biological Psychiatry June 1, 2012 Handan Gunduz-Bruce, Robert M G Reinhart, Brian J Roach et al.

Auditory mismatch negativity (MMN) and P300 event-related potentials (ERPs) are reduced in schizophrenia patients and healthy volunteers administered the N-methyl-D-aspartate glutamate receptor antagonist, ketamine. In rodents, N-acetylcysteine (NAC), a stimulator of the cystine-glutamate exchanger, attenuates the cognitive and behavioral effects of N-methyl-D-aspartate receptor antagonists. On...

DOI: 10.1016/j.biopsych.2011.09.031 Full text