Gamma Oscillations and Excitation/Inhibition Imbalance: Parallel Effects of NMDA Receptor Antagonism and Psychosis.
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging January 18, 2025 Brian J Roach, Judith M. Ford, Spero Nicholas et al. 7 citations
Auditory steady-state response (ASSR) abnormalities in the 40-Hz (gamma band) frequency have been observed in schizophrenia and in rodent studies of NMDA receptor (NMDAR) hypofunction. However, the extent to which 40-Hz ASSR abnormalities in schizophrenia resemble deficits in 40-Hz ASSR induced by acute administration of ketamine, an NMDAR antagonist, is not yet known. To address this knowledge...
DOI: 10.1016/j.bpsc.2025.01.008 (opens in new tab)
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Ketamine
Electroencephalography EEG
Nmda receptor nmdar
Schizophrenia
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