Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention
January 21, 2025
Jennifer L. Schumann, Matthew Di Rago, Noel Woodford et al.
1 citation
Driving under the influence of alcohol and other drugs contributes significantly to road traffic crashes worldwide. This study explored trends of alcohol, methylamphetamine (MA), 3,4-methylenedioxy-N-methylamphetamine (MDMA) and Δ9-tetrahydrocannabinol (THC), in road crashes from 2010 to 2019 in Victoria, Australia. We conducted a cross-sectional analysis using data from the Victorian Institute...
Journal of Analytical Toxicology
March 21, 2023
Dimitri Gerostamoulos, Linda Glowacki, Maria Pricone et al.
9 citations
Six fatalities have occurred from the ingestion of a combination of new psychoactive substances (NPSs), 4-fluoroamphetamine (4FA) and 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) over a 9-month period. Four of these fatalities (one older female and three young males) were from direct adverse effects of drugs, and one each from a fall while being intoxicated...
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
November 30, 2020
Yan Shi, Roujia Wang, Shuai Yuan et al.
Tryptamines are hallucinogenic substances many of which have appeared recently as novel psychoactive substances (NPS). Herein, we describe the establishment of a rapid UHPLC-MS/MS quantitative method for the targeted screening of 16 tryptamines of abuse in hair. Twenty milligram pieces of hair were pulverized below 4 °C in 0.5 mL of deionized water containing 0.1% formic acid and an internal...
Journal of Analytical Toxicology
November 30, 2018
Jeffrey D Pope, Kay Weng Choy, Olaf H Drummer et al.
9 citations
BACKGROUND: Ayahausca is an ethnobotanical drink of South America and the compound dimethyltryptamine (DMT) is primarily responsible for the hallucinogenic effects. DMT has a short half-life and its detection in urinary drug screens is challenging. We investigate a simple alternate approach to detect ayahuasca consumption by relying on other constituents of the drink, the β-carboline harmala...
Forensic Science International
May 20, 2011
Jennifer L. Pilgrim, Dimitri Gerostamoulos, Noel Woodford et al.
44 citations
The use of MDMA (ecstasy) in Australia is a widespread and growing problem, promoting acute toxicity and disease which can lead to premature death in users. We report four cases of fatal serotonin toxicity caused by the combination of MDMA and moclobemide, a reversible MAO-A inhibitor with potent serotonergic activity. Despite the highly reported toxicity of this drug combination, there are...
Journal of Analytical Toxicology
May 1, 2011
Jennifer L. Pilgrim, Dimitri Gerostamoulos, Olaf H Drummer
36 citations
The increasing use of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") and tendency of users to combine MDMA with pharmaceutical agents (especially serotonergic medication) warrants a thorough understanding of MDMA's toxicity profile and potential for drug interactions. This study examined the involvement of MDMA and concurrently administered pharmaceutical drugs in cases reported to the...
Forensic Science International
March 10, 2009
Jochen Beyer, Olaf H Drummer, Hans H Maurer
118 citations
Many plants contain toxic alkaloids which may be dangerous to humans. Despite the large number of poisonous plants, cases of fatal plant poisonings are relatively rare. The frequencies of poisonings and the plants involved are often regionally specific. Plant poisonings can be aggregated into three categories: unintended ingestions, intended ingestions, and poisoning due to abuse of plant...