Recreational drugs 25I-NBOH and 25I-NBOMe bind to both Sudlow's sites I and II of human serum albumin (HSA): biophysical and molecular modeling studies
New Journal of Chemistry January 1, 2021 Wellington Alves de Barros, Marina de Magalhães Silva, Maria Dayanne de Araújo Dantas et al.
The compounds 25I-NBOH and 25I-NBOMe both bind to two distinct sites (site I and site II) on human serum albumin (HSA), a protein that transports substances in the blood. This dual binding may influence how these compounds are distributed throughout the body and how they exert their effects.