Mapping the subcortical connectivity of the human default mode network
bioRxiv July 14, 2021 Jian Li, W. Curley, B. Guérin et al. preprint
The default mode network (DMN) mediates self-awareness and introspection, core components of human consciousness. Therapies to restore consciousness in patients with severe brain injuries have historically targeted subcortical sites in the brainstem, thalamus, hypothalamus, basal forebrain, and basal ganglia, with the goal of reactivating cortical DMN nodes. However, the subcortical...