Quality of life is related to the functional connectivity of the default mode network at rest.
Brain Imaging and Behavior October 1, 2019 Inessa Kraft, Joana Bisol Balardin, João Ricardo Sato et al.
In a cross-sectional study of 42 healthy female working managers, social quality of life was significantly associated with functional connectivity of the default mode network (DMN) at rest. Higher social quality of life scores corresponded to reduced connectivity between the right and left lateral parietal regions of the DMN. The study examined four quality of life domains—physiological, psychological, social, and environmental—but only the social domain showed a link to DMN connectivity. This is described as the first analysis of neural correlates of quality of life in the brain, though limited to a female subgroup.