Hironobu Fujiwara

2 papers in the library · publishing 2025-2026

Papers

Default mode network hub disruption links problematic use of the Internet to brain network disorganization.

Comprehensive Psychiatry July 1, 2026 Nagara Takao, Naoya Oishi, Qi Dai et al.

Problematic use of the internet (PUI) is linked to altered brain network organization through its effect on the default mode network (DMN). In 190 healthy adults aged 20–69, higher PUI severity correlated with reduced functional connectivity among DMN regions. This reduced DMN connectivity strongly predicted changes in whole-brain network properties, including decreased clustering and local efficiency, and increased global efficiency and shorter path lengths—indicating a shift away from optimal small-world network organization. Mediation analyses showed that DMN connectivity substantially mediated the relationship between PUI severity and these network metrics, suggesting that DMN hub disruption is a key pathway by which PUI affects global brain network topology.

DOI: 10.1016/j.comppsych.2026.152725 Full text Default mode network Graph theory Mediation analysis Network hubs +1

Alterations of the default mode network, salience network, and frontoparietal network in non-problematic Internet use and their association with mood regulation: from an internet literacy perspective

Frontiers in Neuroscience July 1, 2025 Mami Shibata, Kosuke Tsurumi, Kei Kobayashi et al.

In healthy volunteers without problematic internet use, higher scores on a mood regulation subscale were associated with stronger functional connectivity between brain networks involved in emotion and cognitive control—specifically the salience, central executive, and default mode networks—and with weaker connectivity between the default mode and frontoparietal networks. These patterns are opposite to those seen in problematic internet use, suggesting that non-problematic internet use may support healthy emotion regulation through distinct brain connectivity changes.

DOI: 10.3389/fnins.2025.1599987