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Chao Wang

2 papers in the library · publishing 2021

Papers

Body-mind relaxation meditation modulates the thalamocortical functional connectivity in major depressive disorder: a preliminary resting-state fMRI study.

Translational Psychiatry October 23, 2021 Fangfang Chen, Xueyu Lv, Jiliang Fang et al.

Body-mind relaxation meditation (BMRM) alters thalamocortical functional connectivity in medication-naive adolescents with major depressive disorder (MDD) and healthy controls. Before the intervention, MDD patients showed reduced connectivity between the bilateral precuneus/posterior cingulate cortex and specific thalamus subregions, and increased connectivity between the left occipital thalamus and left medial frontal cortex. After BMRM, these aberrant connections normalized in MDD patients, and both groups showed decreased connectivity between the left rostral temporal thalamus and left inferior occipital region. These changes suggest BMRM may strengthen connections between the thalamus and default mode network, which support attention and self-related processes. The small sample size limits generalizability.

DOI: 10.1038/s41398-021-01637-8 (opens in new tab) Full text (opens in new tab)

Default mode network-basal ganglia network connectivity predicts the transition to postherpetic neuralgia

Ying Wu, Chao Wang, Wei Qian et al.

Abnormal connections between brain networks, specifically between the default mode network (DMN) and the basal ganglia network (BGN), are linked to the development of chronic pain after shingles. In a cross-sectional study of 92 patients, those with long-term pain (postherpetic neuralgia) showed stronger DMN-BGN connectivity than patients who recovered or were in the acute phase. Among acute patients, this connectivity pattern predicted pain persistence with 77.8% sensitivity and 63.2% specificity, suggesting it may serve as a neuroimaging biomarker for prognosis.

DOI: 10.21203/rs.3.rs-4842138/v1 (opens in new tab)