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Arjan Singh Puniani

2 papers in the library · publishing 2025

Papers

Conscious active inference I: A quantum model naturally implements the path integral needed for real-time planning and control.

Computational and Structural Biotechnology Journal January 1, 2025 Michael C Wiest, Arjan Singh Puniani

Active inference, a framework for modeling how sentient agents optimize behavior and learning, requires probabilistic computations including a path integral over future trajectories. Classical biophysical neural models like Hodgkin-Huxley neurons are unlikely to perform these computations quickly enough in realistic contexts. The path integral underlying active inference is mathematically equivalent to quantum dynamics, suggesting a quantum model provides a natural mechanistic implementation. This first of two companion papers argues that classical neurons are insufficient for temporally deep active inference, while a quantum model offers a biologically plausible alternative. The second paper reviews evidence supporting the Orch OR quantum theory of consciousness in microtubules, explaining discrete perceptual inference cycles.

Conscious active inference II: Quantum orchestrated objective reduction among intraneuronal microtubules naturally accounts for discrete perceptual cycles.

Computational and Structural Biotechnology Journal January 1, 2025 Michael C Wiest, Arjan Singh Puniani

Classical neural models for conscious active inference lack biological plausibility because they cannot explain the discrete, non-overlapping cycles of perceptual inference observed in the brain. The Orchestrated Objective Reduction (Orch OR) theory of consciousness, which treats consciousness as a collective quantum property of microtubules inside neurons, naturally accounts for these cycles. Evidence for this quantum model includes room-temperature quantum effects in microtubules, microtubule resonances that control neuron firing, volatile anesthetics causing unconsciousness by targeting microtubules, and direct biophysical evidence of a macroscopic entangled state in the living human brain. Microtubules thus provide a biologically specific substrate for implementing conscious active inference.