PNAS NexusMarch 1, 2026Lina Jeantin, Pierre Bourdillon, Marc Guenot et al.
Electroencephalography (EEG) signal complexity reflects the richness of brain activity and is considered a marker of consciousness. However, its normative values across physiological conscious states using intracranial EEG (iEEG) across cortical areas remain poorly defined. We aimed at referencing iEEG complexity in the human brain and its links with global states of consciousness. We analyzed...
Purpose of the study: The objective of this study is to evaluate subjective changes in sleep, insomnia, and dream production in chronic benzodiazepine (BZ) users enrolled in a withdrawal program. BZs, widely prescribed to treat insomnia, are likely to alter sleep structure. This research aims to determine the extent to which discontinuing these treatments promotes the restoration of sleep and...
Thalamic and cortical activities are assumed to be time-locked throughout all vigilance states. Using simultaneous intracortical and intrathalamic recordings, we demonstrate here that the thalamic deactivation occurring at sleep onset most often precedes that of the cortex by several minutes, whereas reactivation of both structures during awakening is synchronized. Delays between thalamus and...
This review summarises the results of event-related potentials studies exploring the extent to which the human brain can extract semantic information from external stimuli during sleep. The persistence of a differential response to the subject's own name, relative to any other proper name, during stage 2 (S2) and paradoxical (REM) sleep (PS) suggests that the brain remains able to discriminate...