Translational Psychiatry
April 23, 2026
Jimmy Olusakin, Mahima Dewan, A. Kashyap et al.
Cannabis use during pregnancy is increasing, often to alleviate stress and anxiety, yet the impact of prenatal cannabis exposure alone, or in combination with psychosocial stress on maternal regulation and downstream offspring neurodevelopment remains unclear. Here, we developed a translational rodent model combining prenatal Δ⁹-tetrahydrocannabinol (THC) exposure with chronic psychosocial...
bioRxiv : the preprint server for biology
June 28, 2025
Jimmy Olusakin, Mahima Dewan, Atul Kashyap et al.
preprint
Cannabis use during pregnancy is increasing, often to alleviate stress and anxiety, yet the long-term effect of prenatal cannabis exposure alone or in combination with psychosocial stress on offspring neurodevelopment or maternal behaviors remains unclear. Here, we developed a translational rodent model combining prenatal Δ9-tetrahydrocannabinol (THC) exposure with chronic psychosocial stress...
Nature Neuroscience
September 11, 2019
R. Frau, Vivien Miczán, F. Traccis et al.
The increased legal availability of cannabis has led to a common misconception that it is a safe natural remedy for, among others, pregnancy-related ailments such as morning sickness. Emerging clinical evidence, however, indicates that prenatal cannabis exposure (PCE) predisposes offspring to various neuropsychiatric disorders linked to aberrant dopaminergic function. Yet, our knowledge of how...
Brain Research
December 2, 2015
Dan P Covey, Jennifer M Wenzel, Joseph Cheer
Marijuana is the most popular illegal drug worldwide. Recent trends indicate that this may soon change; not due to decreased marijuana use, but to an amendment in marijuana's illegal status. The cannabinoid type 1 (CB1) receptor mediates marijuana's psychoactive and reinforcing properties. CB1 receptors are also part of the brain endocannabinoid (eCB) system and support numerous forms of...