Concurrent maternal stress and THC exposure during pregnancy alters adolescent behavioral outcomes and corticolimbic molecular programs.
bioRxiv : the preprint server for biology June 28, 2025 Jimmy Olusakin, Mahima Dewan, Atul Kashyap et al. preprint
Cannabis use during pregnancy is increasing, often to alleviate stress and anxiety, yet the long-term effect of prenatal cannabis exposure alone or in combination with psychosocial stress on offspring neurodevelopment or maternal behaviors remains unclear. Here, we developed a translational rodent model combining prenatal Δ9-tetrahydrocannabinol (THC) exposure with chronic psychosocial stress...