Tony Jung

2 papers in the library · publishing 2021-2022

Papers

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Prenatal THC Exposure Induces Sex-Dependent Neuropsychiatric Endophenotypes in Offspring and Long-Term Disruptions in Fatty-Acid Signaling Pathways Directly in the Mesolimbic Circuitry.

eNeuro 2022 Mohammed H Sarikahya, Samantha Cousineau, Marta De Felice et al.

Despite increased prevalence of maternal cannabis use, little is understood regarding potential long-term effects of prenatal cannabis exposure (PCE) on neurodevelopmental outcomes. While neurodevelopmental cannabis exposure increases the risk of developing affective/mood disorders in adulthood, the precise neuropathophysiological mechanisms in male and female offspring are largely unknown....

DOI: 10.1523/eneuro.0253-22.2022 Full text Maldi ims Electrophysiology Lipidomics Mesolimbic system +2

THC and CBD produce divergent effects on perception and panic behaviours via distinct cortical molecular pathways.

Progress in Neuro-Psychopharmacology and Biological Psychiatry January 10, 2021 Hanna J Szkudlarek, Mar Rodríguez-ruiz, Roger Hudson et al.

Clinical and pre-clinical evidence demonstrates divergent psychotropic effects of THC vs. CBD. While THC can induce perceptual distortions and anxiogenic effects, CBD displays antipsychotic and anxiolytic properties. A key brain region responsible for regulation of cognition and affect, the medial prefrontal cortex (PFC), is strongly modulated by cannabinoids, suggesting that these dissociable...

DOI: 10.1016/j.pnpbp.2020.110029 Full text Cannabinoids Latent inhibition Panic Prefrontal cortex