Prenatal THC Exposure Induces Sex-Dependent Neuropsychiatric Endophenotypes in Offspring and Long-Term Disruptions in Fatty-Acid Signaling Pathways Directly in the Mesolimbic Circuitry.
eNeuro 2022 Mohammed H Sarikahya, Samantha Cousineau, Marta De Felice et al.
Despite increased prevalence of maternal cannabis use, little is understood regarding potential long-term effects of prenatal cannabis exposure (PCE) on neurodevelopmental outcomes. While neurodevelopmental cannabis exposure increases the risk of developing affective/mood disorders in adulthood, the precise neuropathophysiological mechanisms in male and female offspring are largely unknown....
DOI: 10.1523/eneuro.0253-22.2022 (opens in new tab)
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Maldi ims
Electrophysiology
Lipidomics
Mesolimbic system
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