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C. Wong

2 papers in the library · publishing 2018-2023

Papers

Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case–control study

Psychological Medicine May 4, 2023 G. Trotta, Victoria Rodriguez, D. Quattrone et al.

Childhood adversity and cannabis use are both known risk factors for psychosis. This study examined whether cannabis use might explain the link between childhood adversity and psychotic disorders. Data from 881 first-episode psychosis patients and 1231 controls from the EU-GEI study showed that household discord was associated with psychosis partly through cannabis use. Lifetime cannabis use mediated 17% of the association, cannabis potency mediated 14%, and frequency of use mediated 29%. Similar results appeared for early exposure to household discord. The findings suggest that harmful cannabis use patterns partially explain how household discord leads to psychosis, and children exposed to challenging home environments could benefit from interventions to prevent cannabis misuse.

DOI: 10.1017/s0033291723000995 (opens in new tab) Full text (opens in new tab) Medicine Psychology

Mindfulness-Based Stress Reduction (MBSR) or Psychoeducation for the Reduction of Menopausal Symptoms: A Randomized, Controlled Clinical Trial

Scientific Reports April 26, 2018 C. Wong, B. Yip, T. Gao et al.

A randomized controlled trial compared Mindfulness-based Stress Reduction (MBSR) with a menopause education control (MEC) in symptomatic peri- and post-menopausal women with mild to moderate symptoms. Both groups reported reduced overall menopausal symptoms on the Greene Climacteric Scale at 8 months. MBSR produced significantly greater reductions on the Anxiety and Depression subscales than MEC, but no differences emerged on other symptom subscales or most secondary outcomes. MBSR appears to reduce psychological symptoms of depression and anxiety beyond active controls but does not reduce somatic, urogenital, or vasomotor symptoms.

DOI: 10.1038/s41598-018-24945-4 (opens in new tab) Full text (opens in new tab) Medicine Psychology