Psilocybin clinical trials: pipeline by phase and status
Every trial in this library's ClinicalTrials.gov slice that names Psilocybin: 299 registered studies, grouped by phase and by recruitment status. For the published research, see the Psilocybin research page.
The pipeline at a glance
| Phase | Trials |
|---|---|
| Early phase 1 | 22 |
| Phase 1 | 90 |
| Phase 1/2 | 19 |
| Phase 2 | 134 |
| Phase 2/3 | 2 |
| Phase 3 | 12 |
| Not applicable | 15 |
| Unspecified | 5 |
| Status | Trials |
|---|---|
| Recruiting or planned | 137 |
| Active, not recruiting | 32 |
| Completed | 90 |
| Stopped | 22 |
| Unknown or other | 18 |
15,384 participants across the 299 trials that report enrollment. The earliest registered start is 2004, and 139 trials started in the last two years.
Most active sponsors
- Johns Hopkins University 32 trials
- Yale University 15 trials
- NYU Langone Health 9 trials
- University of Wisconsin, Madison 9 trials
- Centre for Addiction and Mental Health 8 trials
Evidence by condition
All 299 trials
Most advanced phase first, and within each phase the most recent start date first.
Phase 3 12 trials
-
Recruiting Phase 3 240 participants VA Office of Research and Development Started 2026
Major Depression
-
Recruiting Phase 3 172 participants Centre Hospitalier Universitaire de Nīmes Started 2026
Alcohol Use Disorder, Depressive Sympotoms, Psilocybin
-
Recruiting Phase 3 60 participants Khyber Medical University Peshawar Started 2026
Major Depressive Disorder, Post-Traumatic Stress Disorder (PTSD)
-
Recruiting Phase 3 120 participants Bruyère Health Research Institute. Started 2026
Psychological Distress
-
Recruiting Phase 3 330 participants Cybin IRL Limited Started 2025
Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder, Depression Disorders
-
Completed Phase 3 223 participants Cybin IRL Limited Started 2024
Major Depressive Disorder
-
Recruiting Phase 3 20 participants Sharmin Ghaznavi Started 2024
Major Depressive Disorder
-
Active, not recruiting Phase 3 20 participants University of North Carolina, Chapel Hill Started 2024
Refractory Depression, Treatment Resistant Depression
-
Active, not recruiting Phase 3 238 participants Usona Institute Started 2024
Depressive Disorder, Major
-
Active, not recruiting Phase 3 572 participants COMPASS Pathways Started 2023
Treatment Resistant Depression
-
Completed Phase 3 258 participants COMPASS Pathways Started 2023
Treatment Resistant Depression
-
Completed Phase 3 30 participants University of Washington Started 2022
Burnout, Caregiver, Burnout, Professional, COVID-19, Depression
Phase 2/3 2 trials
-
Recruiting Phase 2/3 300 participants COMPASS Pathways Started 2026
PTSD - Post Traumatic Stress Disorder, PTSD, PTSD Symptoms, PTSD, Post Traumatic Stress Disorder
-
Recruiting Phase 2/3 200 participants NYU Langone Health Started 2023
Advanced Cancer
Phase 2 134 trials
-
Withdrawn Phase 2 0 participants Johns Hopkins University Started 2027
Opioid Use Disorder
-
Not yet recruiting Phase 2 42 participants Peter Hendricks Started 2027
Methamphetamine Use Disorder
-
Not yet recruiting Phase 2 150 participants VA Office of Research and Development Started 2027
Major Depression
-
Not yet recruiting Phase 2 3 participants University of British Columbia Started 2027
Nicotine Dependence
-
Not yet recruiting Phase 2 30 participants University of California, Los Angeles Started 2027
Depression - Major Depressive Disorder, Psilocybin, Cognitive Behavioral Therapy
-
Not yet recruiting Phase 2 150 participants University of New Mexico Started 2026
PTSD, PTSD - Post Traumatic Stress Disorder, Major Depression, Suicidality
-
Not yet recruiting Phase 2 12 participants ARQ National Psychotrauma Centre Started 2026
Posttraumatic Stress Disorder (PTSD)
-
Not yet recruiting Phase 2 48 participants Yale University Started 2026
Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
-
Not yet recruiting Phase 2 36 participants Brigham and Women's Hospital Started 2026
Alcohol Use Disorder
-
Recruiting Phase 2 200 participants National Institute on Aging (NIA) Started 2026
Alzheimer's Disease
-
Not yet recruiting Phase 2 83 participants M.D. Anderson Cancer Center Started 2026
Psilocybin, Neuropathy
-
Not yet recruiting Phase 2 30 participants Nicky Mehtani, MD, MPH Started 2026
Methamphetamine Use Disorder, Human Immunodeficiency Virus (HIV)
-
Not yet recruiting Phase 2 60 participants University of Calgary Started 2026
Advanced Cancer, Demoralization, Existential Distress, Psychological Distress
-
Recruiting Phase 2 30 participants Nantes University Hospital Started 2026
Gambling Disorder
-
Not yet recruiting Phase 2 76 participants University of Calgary Started 2026
Post Traumatic Stress Disorder PTSD, Intimate Partner Violence (IPV)
-
Not yet recruiting Phase 2 20 participants Roswell Park Cancer Institute Started 2026
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
-
Not yet recruiting Phase 2 46 participants University Health Network, Toronto Started 2026
Advanced Cancer, Stage IV Solid Tumor Cancer, Stage IV Sarcoma of Bone, Stage IV Lymphoma
-
Recruiting Phase 2 200 participants NYU Langone Health Started 2026
Alcohol Use Disorder
-
Recruiting Phase 2 30 participants Anthony P King Started 2026
Post Traumatic Stress Disorder, Depression - Major Depressive Disorder
-
Recruiting Phase 2 100 participants Rachel Yehuda Started 2026
Psychological Stress, Depression, Anxiety
-
Recruiting Phase 2 40 participants Region Skane Started 2026
Anorexia Nervosa
-
Recruiting Phase 2 40 participants Yale University Started 2026
Depression, Parkinson's Disease (PD)
-
Recruiting Phase 2 40 participants Centre for Addiction and Mental Health Started 2026
Treatment-Resistant Depression
-
Not yet recruiting Phase 2 10 participants Stanford University Started 2026
Major Depression
-
Recruiting Phase 2 112 participants Centre Hospitalier St Anne Started 2026
Depression - Major Depressive Disorder, Treatment-resistant Depression (TRD)
-
Recruiting Phase 2 90 participants Lakshmi N Yatham Started 2026
Bipolar II Depression
-
Recruiting Phase 2 150 participants Emory University Started 2026
PTSD
-
Not yet recruiting Phase 2 72 participants University of Washington Started 2026
Depression, Anxiety
-
Active, not recruiting Phase 2 15 participants Unity Health Toronto Started 2026
Post Traumatic Stress Disorder, PTSD, Chronic PTSD
-
Not yet recruiting Phase 2 50 participants Washington University School of Medicine Started 2026
Depression
-
Recruiting Phase 2 70 participants Sunstone Medical Started 2026
Post Traumatic Stress Disorder, PTSD
-
Active, not recruiting Phase 2 16 participants University of Washington Started 2026
Anxiety, Depression, Hematopoietic and Lymphatic System Neoplasm, Metastatic Malignant Solid Neoplasm
-
Recruiting Phase 2 128 participants University of Calgary Started 2026
Investigating the Importance of the Subjective Psychedelic Experience
-
Withdrawn Phase 2 0 participants University of New Mexico Started 2026
Suicidal Ideation
-
Not yet recruiting Phase 2 16 participants Kyle Greenway Started 2026
Treatment-Resistant Major Depressive Disorder
-
Recruiting Phase 2 30 participants Centre for Addiction and Mental Health Started 2026
Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD)
-
Not yet recruiting Phase 2 25 participants NYU Langone Health Started 2026
Stuttering
-
Recruiting Phase 2 10 participants Alan Davis Started 2026
Lung Non-Small Cell Carcinoma, Unipolar Depression
-
Recruiting Phase 2 24 participants University of Pennsylvania Started 2025
Opioid Use Disorder
-
Recruiting Phase 2 480 participants NYU Langone Health Started 2025
Opioid Use Disorder
-
Recruiting Phase 2 20 participants Beersheva Mental Health Center Started 2025
Treatment Resistant Depression
-
Recruiting Phase 2 10 participants University of British Columbia Started 2025
Opioid Dependence, Chronic Pain
-
Recruiting Phase 2 36 participants Anna Rose Childress, Ph.D. Started 2025
Opioid Use Disorder
-
Recruiting Phase 2 87 participants Psyence Australia Pty Ltd Started 2025
Adjustment Disorder, Adjustment Disorder With Anxious Mood, Cancer, Cancer Cachexia
-
Recruiting Phase 2 40 participants University of Southern California Started 2025
Mental Health
-
Recruiting Phase 2 15 participants University Health Network, Toronto Started 2025
Caregiver Distress
-
Recruiting Phase 2 10 participants The University of Texas Health Science Center, Houston Started 2025
Bipolar II Disorder, Depression, Bipolar, Suicidality
-
Recruiting Phase 2 108 participants University Medical Center Groningen Started 2025
COPD (Chronic Obstructive Pulmonary Disease), ALS (Amyotrophic Lateral Sclerosis), MS (Multiple Sclerosis), Major Depressive Disorder (MDD)
-
Recruiting Phase 2 80 participants University of Iowa Started 2025
Alcohol Use Disorder, Alcohol Dependence, Alcohol Abuse
-
Active, not recruiting Phase 2 40 participants Nathan Brashares Sackett Started 2025
Alcohol Use Disorder (AUD), PTSD
-
Recruiting Phase 2 50 participants Sunnybrook Health Sciences Centre Started 2025
Depressive Disorder, Major Depressive Disorder
-
Recruiting Phase 2 20 participants M.D. Anderson Cancer Center Started 2025
Depression, Anxiety, Cancer
-
Recruiting Phase 2 50 participants Claudio N Soares Started 2025
Generalized Anxiety Disorder (GAD)
-
Recruiting Phase 2 141 participants Charles Raison Started 2025
Depression
-
Recruiting Phase 2 12 participants Centre for Addiction and Mental Health Started 2025
Treatment Resistant Depression
-
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND) (opens in new tab)
Recruiting Phase 2 16 participants Centre for Addiction and Mental Health Started 2025
Treatment Resistant Depression, Chronic Pain
-
Active, not recruiting Phase 2 16 participants McMaster University Started 2025
Cannabis Use Disorder, Moderate, Cannabis Use Disorder, Severe
-
Recruiting Phase 2 30 participants Unity Health Toronto Started 2025
Chronic Neuropathic Pain, Pain Management
-
Recruiting Phase 2 60 participants Icahn School of Medicine at Mount Sinai Started 2025
Major Depressive Disorder
-
Recruiting Phase 2 15 participants Baylor College of Medicine Started 2025
PTSD
-
Recruiting Phase 2 100 participants Charles S. Grob, M.D. Started 2025
Demoralization
-
Recruiting Phase 2 100 participants University of Texas at Austin Started 2025
Treatment Resistant Depression, MDD, Major Depressive Disorder, Recurrent Depression
-
Completed Phase 2 60 participants Khyber Medical University Peshawar Started 2024
Major Depressive Disorder
-
Recruiting Phase 2 15 participants Beersheva Mental Health Center Started 2024
Obsessive-compulsive Disorder
-
Recruiting Phase 2 40 participants Marissa Raymond-Flesch, MD, MPH Started 2024
Anorexia Nervosa
-
Recruiting Phase 2 120 participants Robin Carhart-Harris, PhD, MA Started 2024
Healthy Participants With Lower-than-average Mental Well-being
-
Active, not recruiting Phase 2 15 participants Yvan Beaussant, MD, MSci Started 2024
Opioid-Related Disorders, Pain Management, Pain Management and Care, Advanced Cancer
-
Unknown status Phase 2 90 participants University of Sydney Started 2024
Alcohol Use Disorder, Alcohol Dependence, Depression, Anxiety
-
Recruiting Phase 2 60 participants Joshua Woolley, MD, PhD Started 2024
Parkinson Disease, Depression
-
Completed Phase 2 20 participants University of Colorado, Denver Started 2024
Major Depressive Disorder, Anhedonia, Treatment Resistant Depression
-
Active, not recruiting Phase 2 15 participants University Health Network, Toronto Started 2024
Advanced Cancer, Stage IV Solid Tumor Cancer, Stage IV Sarcoma of Bone, Stage IV Lymphoma
-
Recruiting Phase 2 100 participants University Hospital, Ghent Started 2024
Treatment Resistant Depression
-
Recruiting Phase 2 100 participants Section for Affective Disorders; Northern Stockholm Psychiatry Started 2024
MDD
-
Recruiting Phase 2 48 participants M.D. Anderson Cancer Center Started 2024
Depression, Anxiety, Psilocybin-Assisted Psychotherapy, Advanced Cancer
-
Recruiting Phase 2 128 participants University of Calgary Started 2024
Alcohol Use Disorder, Alcoholism
-
Unknown status Phase 2 62 participants Brugmann University Hospital Started 2024
Severe Alcohol Use Disorder
-
Recruiting Phase 2 90 participants Johns Hopkins University Started 2024
Opioid Use Disorder
-
Active, not recruiting Phase 2 92 participants University Health Network, Toronto Started 2024
Major Depressive Disorder, Depression, Treatment-Resistant Depression, Mood Disorders
-
Active, not recruiting Phase 2 20 participants Peggy C Nopoulos Started 2024
Alcohol Use Disorder
-
Active, not recruiting Phase 2 14 participants TRYP Therapeutics Started 2024
Irritable Bowel Syndrome
-
Withdrawn Phase 2 0 participants Washington University School of Medicine Started 2024
Major Depressive Disorder
-
Unknown status Phase 2 160 participants Apex Labs Ltd. Started 2023
Post-traumatic Stress Disorder, Depression
-
Withdrawn Phase 2 0 participants Johns Hopkins University Started 2023
Opioid Use Disorder
-
Completed Phase 2 10 participants Centre for Addiction and Mental Health Started 2023
Amnestic Mild Cognitive Impairment
-
Completed Phase 2 10 participants University of Chicago Started 2023
Borderline Personality Disorder, Major Depressive Disorder
-
Recruiting Phase 2 66 participants Johns Hopkins University Started 2023
Tobacco Use Disorder
-
Active, not recruiting Phase 2 56 participants Sunstone Medical Started 2023
Cancer, Major Depressive Disorder
-
Completed Phase 2 17 participants Kevin Boehnke Started 2023
Fibromyalgia
-
Completed Phase 2 60 participants Anders Fink-Jensen, MD, DMSci Started 2023
Alcohol Use Disorder
-
Completed Phase 2 39 participants Rotem Petranker Started 2023
Major Depressive Disorder
-
Withdrawn Phase 2 0 participants Washington University School of Medicine Started 2023
Major Depressive Disorder, Anhedonia
-
Completed Phase 2 41 participants Centre for Addiction and Mental Health Started 2023
Treatment-resistant Depression
-
Unknown status Phase 2 8 participants Combat Stress Started 2023
PTSD
-
Suspended Phase 2 10 participants Nova Mentis Life Science Corp Started 2023
Fragile X Syndrome, Behavior, Cognitive Dysfunction
-
Unknown status Phase 2 10 participants Anders Fink-Jensen, MD, DMSci Started 2023
Alcohol Use Disorder (AUD)
-
Active, not recruiting Phase 2 102 participants COMPASS Pathways Started 2023
Major Depressive Disorder
-
Completed Phase 2 12 participants Ohio State University Started 2023
PTSD, Stress Disorders, Traumatic, Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders
-
Withdrawn Phase 2 0 participants Cybin Therapeutics Inc. Started 2023
Depression, Major Depressive Disorder, Mild Depression, Moderate Depression
-
Completed Phase 2 32 participants COMPASS Pathways Started 2022
Anorexia Nervosa
-
Unknown status Phase 2 20 participants Halucenex Life Sciences Inc. Started 2022
Treatment Resistant Disorders, Post Traumatic Stress Disorder
-
Withdrawn Phase 2 0 participants Massachusetts General Hospital Started 2022
Treatment-Resistant Major Depressive Disorder
-
Withdrawn Phase 2 0 participants Wake Network, Inc. Started 2022
Anxiety and Depression
-
Completed Phase 2 22 participants COMPASS Pathways Started 2022
Post Traumatic Stress Disorder
-
Unknown status Phase 2 128 participants Clairvoyant Therapeutics Started 2022
Alcohol Use Disorder
-
Completed Phase 2 20 participants Sheppard Pratt Health System Started 2022
Treatment Resistant Depression, Suicidal Ideation
-
Completed Phase 2 5 participants TRYP Therapeutics Started 2022
Binge Eating Disorder
-
Completed Phase 2 15 participants Yvan Beaussant, MD, MSci Started 2022
Hospice, Psilocybin, Demoralization, Terminal Illness
-
Active, not recruiting Phase 2 14 participants University of California, San Francisco Started 2022
Bipolar II Disorder
-
Completed Phase 2 30 participants Brain and Cognition Discovery Foundation Started 2021
Treatment Resistant Depression
-
Completed Phase 2 12 participants Joshua Woolley, MD, PhD Started 2021
Parkinson Disease, Depression, Anxiety
-
Completed Phase 2 60 participants King's College London Started 2021
Treatment Resistant Depression
-
Completed Phase 2 144 participants Central Institute of Mental Health, Mannheim Started 2021
Treatment-resistant Depression
-
Completed Phase 2 16 participants University of California, San Diego Started 2021
Anorexia Nervosa
-
Unknown status Phase 2 60 participants National Institute of Mental Health, Czech Republic Started 2021
Treatment Resistant Depression
-
Active, not recruiting Phase 2 90 participants Johns Hopkins University Started 2021
Major Depressive Disorder, Alcohol Use Disorder
-
Unknown status Phase 2 15 participants Sheppard Pratt Health System Started 2021
Treatment Resistant Depression
-
Unknown status Phase 2 27 participants Sheppard Pratt Health System Started 2021
Treatment Resistant Depression
-
Completed Phase 2 12 participants New York State Psychiatric Institute Started 2021
Body Dysmorphic Disorders
-
Active, not recruiting Phase 2 20 participants Keith Heinzerling Started 2021
Alcohol Use Disorder
-
Completed Phase 2 35 participants Section for Affective Disorders; Northern Stockholm Psychiatry Started 2021
Major Depressive Disorder, Depression
-
Unknown status Phase 2 30 participants Maryland Oncology Hematology, PA Started 2020
Major Depressive Disorder
-
Completed Phase 2 19 participants COMPASS Pathways Started 2020
Treatment Resistant Depression
-
Completed Phase 2 37 participants University of Zurich Started 2020
Alcohol Use Disorder
-
Completed Phase 2 347 participants Usona Institute Started 2020
Depressive Disorder, Major
-
Completed Phase 2 55 participants University of Zurich Started 2019
Depressive Disorder, Major
-
Completed Phase 2 233 participants COMPASS Pathways Started 2019
Treatment Resistant Depression
-
Completed Phase 2 59 participants Imperial College London Started 2019
Depressive Disorder, Major
-
Unknown status Phase 2 60 participants University of Helsinki Started 2018
Severe Depression
-
Completed Phase 2 27 participants Johns Hopkins University Started 2017
Major Depressive Disorder
-
Completed Phase 2 40 participants University of Alabama at Birmingham Started 2015
Cocaine-Related Disorders
-
Completed Phase 2 95 participants NYU Langone Health Started 2014
Alcohol Dependence
-
Withdrawn Phase 2 0 participants Multidisciplinary Association for Psychedelic Studies Started 2012
Anxiety, Stage IV Melanoma
-
Completed Phase 2 10 participants University of New Mexico Started 2012
Alcohol Dependence
-
Completed Phase 2 56 participants Johns Hopkins University Started 2007
Depressive Symptoms, Anxiety, Cancer
Phase 1/2 19 trials
-
Not yet recruiting Phase 1/2 50 participants Indiana University Started 2027
Treatment Resistant Depression, Substance Use Disorders
-
Recruiting Phase 1/2 20 participants Johns Hopkins University Started 2026
Mood (Psychological Function), Well Being, Mood, Healthy
-
Not yet recruiting Phase 1/2 20 participants Francisco A Moreno Started 2026
Obsessive - Compulsive Disorder
-
Not yet recruiting Phase 1/2 48 participants Manoj Doss Started 2026
Healthy
-
Recruiting Phase 1/2 30 participants James J. Peters Veterans Affairs Medical Center Started 2026
Spinal Cord Injury, Depression - Major Depressive Disorder, Veteran
-
Recruiting Phase 1/2 50 participants University of California, Los Angeles Started 2026
Major Depressive Diorder
-
Recruiting Phase 1/2 30 participants University of California, San Diego Started 2025
Burnout, Burnout, Healthcare Workers
-
Unknown status Phase 1/2 32 participants Empower Research Inc Started 2025
Psilocybin, Psychotherapy, Group
-
Psilocybe Cubensis Mushrooms With or Without Fluoxetine for Refractory Depression (opens in new tab)
Recruiting Phase 1/2 24 participants Federal University of Latin American Integration Started 2024
Depressive Disorder
-
Active, not recruiting Phase 1/2 20 participants Ottawa Hospital Research Institute Started 2024
Depression, Anxiety, Distress, Emotional
-
Active, not recruiting Phase 1/2 30 participants Joshua Woolley, MD, PhD Started 2023
Chronic Low-back Pain
-
Completed Phase 1/2 55 participants University of Washington Started 2023
Hematopoietic and Lymphatic System Neoplasm, Metastatic Malignant Solid Neoplasm
-
Completed Phase 1/2 57 participants Cybin IRL Limited Started 2022
Major Depressive Disorder
-
Active, not recruiting Phase 1/2 30 participants Portland VA Research Foundation, Inc Started 2022
Amphetamine-Related Disorders
-
Recruiting Phase 1/2 30 participants Johns Hopkins University Started 2022
Healthy
-
Completed Phase 1/2 21 participants Imperial College London Started 2021
Anorexia Nervosa
-
Terminated Phase 1/2 10 participants Gitte Moos Knudsen Started 2020
Cluster Headache
-
Completed Phase 1/2 13 participants Johns Hopkins University Started 2017
Healthy
-
Completed Phase 1/2 12 participants Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Started 2004
Anxiety
Phase 1 90 trials
-
Not yet recruiting Phase 1 70 participants Trent Emerick Started 2027
Pain Management, Postoperative Pain
-
Not yet recruiting Phase 1 80 participants Johns Hopkins University Started 2027
Psilocybin Intoxication
-
Not yet recruiting Phase 1 120 participants University of Wisconsin, Madison Started 2027
Well-Being, Psychological, Psychedelic Experiences
-
Not yet recruiting Phase 1 18 participants University of Minnesota Started 2026
Borderline Personality Disorder, Borderline Personality Pathology, Depressive Symptoms, Emotion Dysregulation
-
Not yet recruiting Phase 1 32 participants MycoMedica Life Sciences PBC Started 2026
Premenstrual Dysphoric Disorder ( PMDD), PMDD
-
Not yet recruiting Phase 1 50 participants Charles Raison Started 2026
Aging, Longevity, Biomarkers of Aging
-
Pilot Study on the Effects of Psilocybin on Belief Updating and Insight Formation (opens in new tab)
Recruiting Phase 1 24 participants Brown University Started 2026
Phase I
-
Recruiting Phase 1 15 participants Oregon Health and Science University Started 2026
Chronic Pelvic Pain
-
Recruiting Phase 1 90 participants NYU Langone Health Started 2026
Anhedonia, Emotional Blunting
-
Not yet recruiting Phase 1 50 participants Gabriella Gobbi Started 2026
Healthy Participants, Placebo - Control, Psilocybin
-
Not yet recruiting Phase 1 51 participants Yale University Started 2026
Loneliness, Grief
-
Recruiting Phase 1 80 participants Jennifer Mitchell Started 2026
Anhedonia in Healthy Volunteers, Older Adults (50-90 Years)
-
Recruiting Phase 1 30 participants Francisco A Moreno Started 2026
Obsessive-Compulsive Disorder
-
Recruiting Phase 1 36 participants University of New Mexico Started 2026
PTSD
-
Recruiting Phase 1 15 participants Gustavo Vazquez Started 2026
Demoralization, Safety
-
Recruiting Phase 1 40 participants University of Colorado, Denver Started 2026
Healthy Volunteer, Older Adults (65-85 Years)
-
Active, not recruiting Phase 1 24 participants Scottsdale Research Institute Started 2026
PTSD
-
Recruiting Phase 1 20 participants Johns Hopkins University Started 2026
Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH)
-
Recruiting Phase 1 10 participants Hadassah Medical Organization Started 2025
Healthy Volunteers
-
Recruiting Phase 1 40 participants University of California, Berkeley Started 2025
Aging
-
Recruiting Phase 1 85 participants Medical University of Vienna Started 2025
Depression - Major Depressive Disorder, Anhedonia
-
Recruiting Phase 1 40 participants Johns Hopkins University Started 2025
Posttraumatic Stress Disorder
-
Recruiting Phase 1 100 participants Johns Hopkins University Started 2025
Psilocybin, Music Intervention
-
Recruiting Phase 1 60 participants University of Wisconsin, Madison Started 2025
Psilocybin
-
Completed Phase 1 20 participants MycoMedica Life Sciences PBC Started 2025
Healthy Volunteer
-
Enrolling by invitation Phase 1 20 participants Joshua Woolley, MD, PhD Started 2025
Chronic Pain
-
Recruiting Phase 1 12 participants Yale University Started 2025
Opioid Use Disorder
-
Recruiting Phase 1 40 participants University of Calgary Started 2025
Persisting Symptoms After Concussion
-
Recruiting Phase 1 16 participants University Hospital, Basel, Switzerland Started 2025
Healthy
-
Completed Phase 1 10 participants Johns Hopkins University Started 2025
Healthy Volunteers
-
Completed Phase 1 24 participants University Hospital, Basel, Switzerland Started 2025
Healthy
-
Recruiting Phase 1 24 participants University Hospital, Basel, Switzerland Started 2025
Healthy
-
Recruiting Phase 1 40 participants University College, London Started 2025
Healthy
-
Recruiting Phase 1 50 participants Johns Hopkins University Started 2025
Psychedelic Effects in Healthy Volunteers
-
Recruiting Phase 1 115 participants University of Wisconsin, Madison Started 2025
Healthy, Psychedelic Experiences, Vagus Nerve Stimulation
-
Withdrawn Phase 1 0 participants Johns Hopkins University Started 2025
Post-Traumatic Stress Disorder
-
Completed Phase 1 17 participants Johns Hopkins University Started 2024
Psychedelic Experiences
-
Recruiting Phase 1 20 participants University of Colorado, Denver Started 2024
Breast Cancer, Ovarian Cancer
-
Completed Phase 1 15 participants University of Washington Started 2024
Hematopoietic and Lymphatic System Neoplasm, Metastatic Malignant Solid Neoplasm
-
Recruiting Phase 1 12 participants Johns Hopkins University Started 2024
Cannabis Use Disorder
-
Completed Phase 1 16 participants MycoMedica Life Sciences PBC Started 2024
Healthy Volunteers
-
Active, not recruiting Phase 1 18 participants Centre for Addiction and Mental Health Started 2024
Treatment Resistant Depression, Autism Spectrum Disorder
-
Recruiting Phase 1 50 participants Yale University Started 2024
Transdiagnostic, Depression - Major Depressive Disorder, Anxiety, PTSD Symptoms
-
Active, not recruiting Phase 1 30 participants University Health Network, Toronto Started 2024
Bipolar Depression
-
Completed Phase 1 10 participants Centre for Addiction and Mental Health Started 2024
Obsessive-Compulsive Disorder
-
Active, not recruiting Phase 1 20 participants Johns Hopkins University Started 2024
Post Traumatic Stress Disorder
-
Recruiting Phase 1 40 participants Johns Hopkins University Started 2024
Chronic Low-back Pain, Depression
-
Completed Phase 1 24 participants MycoMedica Life Sciences PBC Started 2024
Healthy Volunteers
-
Recruiting Phase 1 80 participants University of California, Berkeley Started 2024
Perception Disorders
-
Completed Phase 1 6 participants University of Wisconsin, Madison Started 2023
Healthy, Psychedelic Experiences, Sleep
-
Completed Phase 1 122 participants University of Zurich Started 2023
Healthy
-
Unknown status Phase 1 30 participants NWTraumatherapies Started 2023
Trauma, Nervous System
-
Completed Phase 1 24 participants University Hospital, Basel, Switzerland Started 2023
Healthy
-
Active, not recruiting Phase 1 12 participants Robin Carhart-Harris, PhD, MA Started 2023
Psychedelic Experiences, Neuroimaging, Healthy Volunteers
-
Active, not recruiting Phase 1 28 participants Yale University Started 2023
Obsessive-Compulsive Disorder
-
Completed Phase 1 16 participants University of California, Los Angeles Started 2023
Major Depressive Disorder
-
Completed Phase 1 10 participants Lobe Sciences Ltd. Started 2023
Side Effect of Drug
-
Withdrawn Phase 1 0 participants University of Wisconsin, Madison Started 2023
Healthy
-
Completed Phase 1 18 participants University of Nebraska Started 2023
Pancreas Cancer, Biliary Tract Cancer, Psychological Distress, Gastrointestinal Cancer
-
Terminated Phase 1 5 participants University of Wisconsin, Madison Started 2023
Methamphetamine Use Disorder, Substance-Related Disorders, Chemically-Induced Disorders, Substance Use Disorders
-
Completed Phase 1 24 participants University of Utah Started 2023
Depression, Burnout, Professional
-
Completed Phase 1 11 participants Emory University Started 2022
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
-
Completed Phase 1 19 participants Imperial College London Started 2022
Obsessive-Compulsive Disorder
-
Active, not recruiting Phase 1 10 participants University of California, San Diego Started 2022
Phantom Limb Pain
-
Completed Phase 1 20 participants Johns Hopkins University Started 2022
Post-Treatment Lyme Disease, Chronic Lyme Disease, Lyme Disease, Chronic
-
Completed Phase 1 60 participants Usona Institute Started 2022
QTc Interval, Pharmacokinetics
-
Unknown status Phase 1 20 participants University of California, San Francisco Started 2022
Healthy
-
Completed Phase 1 56 participants Diamond Therapeutics Inc. Started 2021
Healthy Controls
-
Terminated Phase 1 10 participants University of Minnesota Started 2021
Perception Disturbance, Visual Suppression, Psychedelic Experiences
-
Terminated Phase 1 4 participants Beckley Psytech Limited Started 2021
Short Lasting Unilateral Neuralgiform Headache Attacks
-
Completed Phase 1 18 participants Yale University Started 2021
Migraine Headache
-
Completed Phase 1 8 participants University of Wisconsin, Madison Started 2021
Psychedelic Experiences, Amnesia
-
Recruiting Phase 1 10 participants University of Wisconsin, Madison Started 2021
Opioid Use Disorder
-
Completed Phase 1 32 participants University Hospital, Basel, Switzerland Started 2020
Healthy
-
Completed Phase 1 22 participants Johns Hopkins University Started 2019
Anorexia Nervosa
-
Completed Phase 1 27 participants University Hospital, Basel, Switzerland Started 2019
Healthy
-
Terminated Phase 1 12 participants Yale University Started 2019
Post-Traumatic Headache
-
Completed Phase 1 15 participants University of Arizona Started 2019
Obsessive-compulsive Disorder (OCD)
-
Completed Phase 1 28 participants Yale University Started 2018
Obsessive-Compulsive Disorder
-
Active, not recruiting Phase 1 18 participants Yale University Started 2018
Major Depressive Disorder
-
Completed Phase 1 30 participants Joshua Woolley Started 2018
Distress, Depression, Grief
-
Completed Phase 1 14 participants Yale University Started 2017
Migraine Headache
-
Recruiting Phase 1 200 participants Gitte Moos Knudsen Started 2017
Basic Science
-
Completed Phase 1 25 participants Yale University Started 2016
Cluster Headache
-
Completed Phase 1 12 participants NYU Langone Health Started 2015
Religious or Spiritual Problem
-
Completed Phase 1 24 participants Johns Hopkins University Started 2015
Healthy
-
Completed Phase 1 12 participants University of Wisconsin, Madison Started 2014
Healthy
-
Completed Phase 1 40 participants Johns Hopkins University Started 2014
Healthy
-
Completed Phase 1 10 participants Johns Hopkins University Started 2013
Psilocybin, Hallucinogens, Pharmacologic Actions, Central Nervous System Agents
-
Completed Phase 1 75 participants Johns Hopkins University Started 2009
Healthy
Early phase 1 22 trials
-
Suspended Early Phase 1 10 participants University of California, Los Angeles Started 2029
Cocaine Use Disorder
-
Not yet recruiting Early Phase 1 20 participants Yale University Started 2026
Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI
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Recruiting Early Phase 1 18 participants Johns Hopkins University Started 2026
Psychedelic Effects in Healthy Volunteers
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Not yet recruiting Early Phase 1 10 participants NYU Langone Health Started 2026
IBS - Irritable Bowel Syndrome
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Recruiting Early Phase 1 10 participants Yale University Started 2026
Smokers With Chronic Pain
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Recruiting Early Phase 1 100 participants Pontifícia Universidade Católica do Rio de Janeiro Started 2026
Healthy Adults
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Recruiting Early Phase 1 12 participants University of Virginia Started 2026
Prolonged Grief Disorder
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Recruiting Early Phase 1 30 participants Imperial College London Started 2025
Self Harm
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Recruiting Early Phase 1 13 participants Tel-Aviv Sourasky Medical Center Started 2025
Post-Traumatic Stress Disorder, PTSD
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Recruiting Early Phase 1 50 participants Yale University Started 2025
Migraine
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Recruiting Early Phase 1 24 participants Johns Hopkins University Started 2025
Amyotrophic Lateral Sclerosis
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Recruiting Early Phase 1 20 participants Kevin Murnane Started 2025
Methamphetamine Use Disorder
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Recruiting Early Phase 1 30 participants University of Alabama at Birmingham Started 2023
Fibromyalgia, Primary
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Unknown status Early Phase 1 64 participants The Roots to Thrive Society for Psychedelic Therapy Started 2023
End of Life
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Withdrawn Early Phase 1 0 participants University of Alabama at Birmingham Started 2023
Demoralization
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Withdrawn Early Phase 1 0 participants Optimi Health Corporation Started 2023
Mood Disturbance, Mood Change, Sleep Disturbance, Drug Effect
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Active, not recruiting Early Phase 1 35 participants Johns Hopkins University Started 2022
Obsessive-Compulsive Disorder
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Completed Early Phase 1 12 participants University of Utah Started 2021
Cancer
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Completed Early Phase 1 11 participants Washington University School of Medicine Started 2021
Psilocybin
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Recruiting Early Phase 1 20 participants Johns Hopkins University Started 2021
Depressive Symptoms, Depression, Alzheimer Disease, Mild Cognitive Impairment
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Completed Early Phase 1 28 participants University Hospital, Basel, Switzerland Started 2019
Healthy
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Completed Early Phase 1 29 participants NYU Langone Health Started 2009
Cancer
Not applicable 15 trials
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Enrolling by invitation 65 participants Joshua Rosenblat Started 2026
Treatment-resistant Depression (TRD)
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Completed 4 participants Centre Hospitalier Universitaire de Nīmes Started 2024
Psychogenic Nonepileptic Seizures, Psilocybin
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Completed 10 participants Centre Hospitalier Universitaire de Nīmes Started 2024
Depressive Disorder, Depressive Disorder, Treatment-Resistant, Hallucinogens, Reinforcement, Psychology
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Unknown status 30 participants Western University, Canada Started 2024
Disorders of Consciousness, Psychedelic Experiences
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Withdrawn 0 participants National University of Natural Medicine Started 2024
Meditation, Microdosing
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Completed 20 participants Matthew Hicks Started 2024
Depression
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Recruiting 35 participants Maastricht University Started 2024
Fibromyalgia
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Completed 20 participants King's College London Started 2024
Functional Neurological Disorder
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Completed 30 participants Centre Hospitalier Universitaire de Nīmes Started 2024
Alcohol-Related Disorders, Depressive Disorder, Addiction
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Completed 5 participants University of Otago Started 2023
Depressive Disorder, Treatment-Resistant
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Completed 67 participants King's College London Started 2022
Autism Spectrum Disorder
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Enrolling by invitation 48 participants Felix Mueller Started 2022
Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
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Completed 34 participants National Council of Scientific and Technical Research, Argentina Started 2021
Cognitive Change, Creativity, Mood Change, Sleep
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Completed 140 participants University of Zurich Started 2013
Healthy
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Completed 82 participants Johns Hopkins University Started 2008
Nicotine Dependence
Unspecified 5 trials
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Active, not recruiting 20 participants Healing Advocacy Fund Started 2025
Alcohol Use Disorder
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Psilocybin in Patients With Fibromyalgia: EEG-measured Brain Biomarkers of Action (opens in new tab)
Unknown status 20 participants Imperial College London Started 2022
Fibromyalgia
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Active, not recruiting 46 participants King's College London Started 2021
Depression - Major Depressive Disorder
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Terminated 26 participants Usona Institute Started 2020
Major Depressive Disorder
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Active, not recruiting 376 participants University Hospital, Geneva Started 2020
Major Depressive Disorder (MDD), Anxiety Disorders, Substance Use Disorder (SUD), PTSD - Post Traumatic Stress Disorder
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