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Psilocybin and psychedelic-assisted therapy: all studies

Page 17 of 25: studies 161 to 170 of 248, newest first. Back to the psilocybin and psychedelic-assisted therapy overview

Research

Ethical considerations for psychedelic-assisted therapy in military clinical settings

Journal of Medical Ethics May 30, 2023 Scott Hoener, Aaron Wolfgang, David A. Nissan et al. 6 citations

Psychedelic treatments, particularly 3,4-methylenedioxymethamphetamine (MDMA)-assisted and psilocybin-assisted therapies, have recently seen renewed interest in their clinical potential to treat various mental health conditions. Clinical trials for both MDMA-assisted and psilocybin-assisted therapies have shown to be highly efficacious for post-traumatic stress disorder and major depression....

DOI: 10.1136/jme-2023-108943 (opens in new tab) Psilocybin Military personnel Mental health Clinical trial +3

Psilocybin-assisted psychotherapy as a potential treatment for eating disorders: a narrative review of preliminary evidence

Trends in Psychiatry and Psychotherapy May 1, 2023 Elena Koning, Elisa Brietzke 13 citations

Eating disorders (ED) are a group of potentially severe mental disorders characterized by abnormal energy balance, cognitive dysfunction, and emotional distress. Cognitive inflexibility is a major challenge to successful ED treatment and dysregulated serotonergic function has been implicated in this symptomatic dimension. Moreover, there are few effective treatment options and long-term...

Study protocol of an open-label proof-of-concept trial examining the safety and clinical efficacy of psilocybin-assisted therapy for veterans with PTSD

BMJ Open May 1, 2023 Alan K. Davis, Adam W. Levin, Paul Nagib et al. 19 citations

Introduction Psilocybin-assisted therapy has shown significant promise in treating the cluster of mood and anxiety symptoms that comprise post-traumatic stress disorder (PTSD) but has yet to be tested specifically in this condition. Furthermore, current pharmacological and psychotherapeutic treatments for PTSD are difficult to tolerate and limited in efficacy, especially in the US Military...

A Phase I trial to inform clinical protocols for the safe administration of psilocybin-assisted psychotherapy

medRxiv April 19, 2023 Jennifer Bennett, Michael D. Blough, Ian Mitchell et al. 3 citations preprint

Abstract This Phase I trial aims to inform the development of safety protocols for psilocybin-assisted therapy. Psychedelics, including psilocybin, are increasingly being recognized as a successful treatment option for many mental health concerns. In order to decrease the risks associated with its clinical use, more data is required regarding its physiological effects in healthy individuals....

Optimizing outcomes in psilocybin therapy: Considerations in participant evaluation and preparation.

Journal of Affective Disorders April 1, 2023 Nadav Liam Modlin, Tammy M Miller, James J Rucker et al. 30 citations

Recent studies have demonstrated the promise of psilocybin therapies in creating positive changes for those with poor mental health across multiple diagnostic categories, including major depressive disorder (MDD), end-of-life anxiety, and obsessive-compulsive disorder (OCD). While there may be a large population that is eligible to participate in psilocybin therapy based on psychiatric...

DOI: 10.1016/j.jad.2023.01.077 (opens in new tab) Full text (opens in new tab) Psychedelic therapy Optimizing psychedelics Treatment outcomes Psilocybin treatment +3

Psychotherapy with Psilocybin for Depression: Systematic Review

Behavioral Sciences March 31, 2023 Jonathan Joseph Dawood Hristova, Virtudes Pérez-Jover 39 citations

Depression is a common mental health issue that affects 280 million people in the world with a high mortality rate, as well as being a leading cause of disability. Psychopharmacological therapies with psychedelics, particularly those with psilocybin, are showing promising potential for the treatment of depression, among other conditions. Some of their benefits include a rapid and exponential...

Exploring psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder

Frontiers in Psychiatry March 14, 2023 Jonathan Brett, Elizabeth Knock, Paul Liknaitzky et al. 16 citations

Methamphetamine use disorder is a chronic relapsing condition associated with substantial mental, physical, and social harms and increasing rates of mortality. Contingency management and psychotherapy interventions are the mainstays of treatment but are modestly effective with high relapse rates, while pharmacological treatments have shown little to no efficacy. Psilocybin-assisted...

DOI: 10.3389/fpsyt.2023.1123424 (opens in new tab) Psilocybin Methamphetamine Psychotherapist Hallucinogen +2

Underground small-group therapy of treatment-resistant depression and complex post-traumatic stress disorder (C-PTSD) with psilocybin—A retrospective case study

March 10, 2023 Mika Turkia 9 citations preprint

While a relatively large body of research exists on many aspects of psychedelic therapy, articles describing a complete, successful treatment process are rarely found. This article therefore presents a case of a woman in her early forties with early complex trauma due to domestic violence, sexual abuse and poverty in her childhood, resulting in approximately three decades of treatment resistant...

Research into Psychedelic-Assisted Psychotherapy for Anorexia Nervosa Should be Funded.

Journal of Bioethical Inquiry March 1, 2023 Lauren S Otterman 9 citations

Eating disorders are debilitating diseases that have twin impacts on the body and mind and are associated with a number of physiological and psychological comorbidities (Blinder, Cumella, and Sanathara 2006; Casiero and Frishman 2006), including increased suicide risk (Arcelus et al. 2011; Lipson and Sonneville 2020). In addition, eating disorders are growing in prevalence (Gilmache et al....