Insight - a sudden change in understanding or perspective that feels true or reliable - is a common occurrence during psychedelic experiences, and often considered by clinicians and patients to be central to their therapeutic value. However, their occurrence and role has not been systematically assessed. We reviewed all peer-reviewed studies that published data on insight catalysed by a classic...
Psilocybin, a serotonergic psychedelic, may have therapeutic benefits for Substance Use Disorders (SUDs), but its overall efficacy and safety remain uncertain. This systematic review assessed the safety and efficacy of psilocybin for SUDs through a systematic database search conducted via OVID on May 22, 2024, and summarized 26 ongoing clinical trials registered on clinicaltrials.gov. Among 16...
Many scholars have claimed that the skills depicted by Zhuangzi can lead to self-transcendence of experiencing and attaining the Dao. However, this view is open to question. Based on a comprehensive reading of the received text of Zhuangzi, this paper attempts a comprehensive reinterpretation of its allegories of skills, including “Cook Ding Butchering an Ox”, “The Hunchback Catching Cicadas”,...
This article examines the complex interplay between language, meaning, and divine revelation in Jewish textual traditions through comparative analysis of diverse interpretative frameworks: the intellectual approach of Rabbi Chaim of Volozhin, the hermeneutics of religious passion and restraint developed by the Netziv (Rabbi Naftali Zvi Yehuda Berlin), the contemporary philosophical perspectives...
This article explores the domain of occultism, with a particular emphasis on the occurrences of spirit possession and the associated Christian healing rituals observed in modern Indonesia. The research posits that malevolent entities, including the devil and evil spirits, are integral to religious belief systems and significantly impact individuals' lives. To substantiate this claim, the study...
medRxivMay 29, 2025Paul B. Fitzgerald, Sara Webb, Nigel Christopher Denning et al.2 citations
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Abstract Objective Despite many decades of experimental studies and clinical trials involving a variety of psychedelic agents, we still lack a comprehensive understanding of the effects of these substances on psychological experiences. As such, we designed and conducted a study to comprehensively characterise the effects of both psilocybin and 3,4-Methylenedioxymethamphetamine (MDMA) on a range...
O uso terapêutico de psicodélicos tem ganhado crescente interesse na psiquiatria, principalmente no tratamento de transtornos mentais resistentes a terapias convencionais, como a depressão resistente e a ansiedade. Este artigo de revisão aborda os fundamentos bioquímicos, a segurança e as indicações emergentes de psicodélicos, como ayahuasca, DMT, psilocibina e LSD, com foco nos mecanismos...
Chanting is a universal practice with deep ethnocultural roots. More recently, chanting has become popular on online platforms and meditation apps which have extended chanting practices beyond their original cultural, sacred, and healing traditions. The aim of the current study was to determine if online chanting meditation promotes altered states of consciousness and psychosocial benefits when...
Suhrawardi (1154-1191) is one of the leading philosophers in the Islamic philosophical tradition who introduced the Philosophy of Illumination (Hikmat al-Ishraq) as a synthesis between Peripatetic rationalism and mystical experience. Suhrawardi emphasized that enlightenment (isyraq) through intuitive experience has a fundamental role in understanding reality. The main concept in his philosophy...
The purpose of the present study is to determine feasibility and acceptability of a standardized hypnosis intervention for a mystical experience based on a conceptual framework including cognitive expectancy, demand characteristics, the induced hypnotic state, and the role of hypnotizability. Ten college student participants provided informed consent and received a hypnotic induction and...