Efficacy and safety of psilocybin for the treatment of substance use disorders: A systematic review.
Neuroscience & Biobehavioral Reviews June 1, 2025 Shakila Meshkat, Gunjan Malik, Richard J. Zeifman et al. 11 citations
Psilocybin, a serotonergic psychedelic, may have therapeutic benefits for Substance Use Disorders (SUDs), but its overall efficacy and safety remain uncertain. This systematic review assessed the safety and efficacy of psilocybin for SUDs through a systematic database search conducted via OVID on May 22, 2024, and summarized 26 ongoing clinical trials registered on clinicaltrials.gov. Among 16...
DOI: 10.1016/j.neubiorev.2025.106163 (opens in new tab)
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Psychedelic-assisted psychotherapy
Psychedelic therapy
Addiction treatment
Substance use disorders
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