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MDMA: all studies

Page 285 of 345: studies 2,841 to 2,850 of 3,446, newest first. Back to the MDMA overview

Research

Mystical Experience in Emily Dickinson's Later Poems

JOURNAL OF LANGUAGE STUDIES October 8, 2023 Atyaf Abdel-Rezzaq Hemad, Hamdi Hameed Al-Douri

This paper is mainly concerned with mystical experience in Emily Dickinson's later poems (composed between 1864 and 1886) to show the poet's spiritual growth and her attitude to the love of the Divine. It aims at analyzing and interpreting the poetry of Emily Dickinson from a mystical point of view. Most of Dickinson's poems trace themes like death, love and spiritual ecstasy. It proposes that...

Pharmacists and psychedelic medicine

JACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY October 1, 2023 Kelan Thomas

In coming years, pharmacists will begin fielding more questions regarding psychedelic medicine, most notably with the imminent FDA approval of 3,4-methylenedioxymethamphetamine (MDMA) for posttraumatic stress disorder (PTSD) expected in 2024 and psilocybin for major depressive disorder (MDD) likely in 2025. Psychedelics are unique medications in many ways, but especially due to the mental...

Case analysis of long-term negative psychological responses to psychedelics

Scientific Reports September 25, 2023 Rebecka Bremler, Nancy Katati, Parvinder Shergill et al. 102 citations

Abstract Recent controversies have arisen regarding claims of uncritical positive regard and hype surrounding psychedelic drugs and their therapeutic potential. Criticisms have included that study designs and reporting styles bias positive over negative outcomes. The present study was motivated by a desire to address this alleged bias by intentionally focusing exclusively on negative outcomes,...

DOI: 10.1038/s41598-023-41145-x (opens in new tab) Full text (opens in new tab) Thematic analysis Qualitative research Salient Clinical psychology

O PAPEL DOS ALUCINÓGENOS NO TRATAMENTO DE TRANSTORNOS MENTAIS E SUA RELEVÂNCIA NA PSIQUIATRIA: UMA REVISÃO INTEGRATIVA

Revista Ibero-Americana de Humanidades, Ciências e Educação September 22, 2023 Júlia Ruys Mattos Queiroz da Silva, Marcos Antônio Mendonça 2 citations

Este trabalho apresenta uma análise sobre a terapia psicodélica como uma possível abordagem para tratamentos psiquiátricos, visando a saúde mental, explorando suas raízes históricas, fundamentos neurobiológicos e resultados clínicos. A revisão da literatura revela que substâncias psicodélicas, como a psilocibina e o MDMA (ecstasy), demonstram um potencial terapêutico promissor para transtornos...

Drug adulteration and substitution within Australian cryptomarkets: An analysis of Test4Pay

September 21, 2023 Monica J Barratt, Matthew Ball, Gabriel T. W. Wong et al. 1 citation

Prohibited drugs in unregulated markets are often adulterated, resulting in increased risks for consumers. This study investigated levels of drug adulteration and substitution in drugs purchased by Australians from cryptomarkets.Methods.Data were collected from the Dread subforum /d/Test4Pay from 1/9/2022 to 23/8/2023. Posts were included if they reported the results of drug samples submitted...

Lifeboat ethics, risk, and therapeutic opportunity: an appeal for equitable psychedelic therapy access in the “high-risk” addiction patient

Frontiers in Psychiatry September 20, 2023 Taylor Black 2 citations

Psychedelic-assisted treatment (PAT) for mental health is in renaissance. Psilocybin and MDMA stand near FDA approval, and US cities and states are decriminalizing or regulating the non-clinical use of psilocybin. However, neither FDA indications nor a regulated use model sufficiently address the complex needs and opportunities for an improved treatment of addiction. When paired with disability...

DOI: 10.3389/fpsyt.2023.1159843 (opens in new tab) Addiction Population Mental illness Legalization +6

Tryptamines and Mental Health: Activating the 5-HT Receptor for Therapeutic Potential

ACS Medicinal Chemistry Letters September 15, 2023 Robert B. Kargbo 11 citations

Tryptamines, a class of 3-aminoethyl-indoles that activate the serotonin receptor, show potential for novel mental health treatments. The FDA has granted "breakthrough therapy designation" to psilocybin and MDMA for treatment-resistant depression, major depressive disorder, and post-traumatic stress disorder, sparking global research efforts. Various clinical trials are currently investigating...

DOI: 10.1021/acsmedchemlett.3c00390 (opens in new tab) Full text (opens in new tab) Tryptamines 5-HT Receptor Pharmacology Data science

Effects of Serial Polydrug Use on the Rewarding and Aversive Effects of the Novel Synthetic Cathinone Eutylone

Brain Sciences September 7, 2023 Hayley N. Manke, Samuel S. Nunn, Agnieszka Sulima et al. 6 citations

BACKGROUND: As individual synthetic cathinones become scheduled and regulated by the Drug Enforcement Administration (DEA), new ones regularly are produced and distributed. One such compound is eutylone, a novel third-generation synthetic cathinone whose affective properties (and abuse potential) are largely unknown. The following experiments begin to characterize these effects and how they may...

Tusi: a new ketamine concoction complicating the drug landscape.

The American Journal of Drug and Alcohol Abuse September 3, 2023 Joseph J Palamar 29 citations

A drug concoction called tusi has emerged in Latin America and in Europe and is now beginning to acquire popularity in the United States. "Tusi" is a phonetic translation of "2C," a series of psychedelic phenethylamines. The concoction is also sometimes referred to as "pink cocaine" as it typically comes in the form of pink powder. However, despite its name, the concoction rarely contains 2C...

Effects of ambient temperature on locomotor activity and place conditioning elicited by abused psychostimulants in mice: Role of 3,4-methylenedioxy moiety.

Drug and Alcohol Dependence September 1, 2023 Brenda M. Gannon, Lauren R Fitzgerald, Christopher O Godwin et al.

Humans often administer psychostimulants in party or music festival settings characterized by warm ambient temperatures, which may impact drug effects; however, preclinical studies rarely investigate drug effects at multiple ambient temperatures. Work with 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxypyrovalerone (MDPV) suggests that the presence of a 3,4-methylenedioxy ring...

DOI: 10.1016/j.drugalcdep.2023.110917 (opens in new tab) Full text (opens in new tab) Ambient temperature Cathinones Conditioned place preference Locomotor activity +2