Page 298 of 448: studies 2,971 to 2,980 of 4,475, newest first. Back to the ketamine overview
Behavioural Brain Research June 6, 2011
Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.
Fundamental and Clinical Pharmacology June 2, 2011 Marko A. Peltoniemi, Teijo I. Saari, Nora M. Hagelberg et al. 44 citations
Ketamine is an intravenous anaesthetic and analgesic agent but it can also be used orally as an adjuvant in the treatment of chronic pain. This study investigated the effect of the herbal antidepressant St John's wort, an inducer of cytochrome P450 3A4 (CYP3A4), on the pharmacokinetics and pharmacodynamics of oral S-ketamine. In a randomized cross-over study with two phases, 12 healthy subjects...
Psychopharmacology June 2011 Anita J Bechtholt-Gompf, Karen L Smith, Catherine S John et al.
In patients, ketamine is a fast-acting antidepressant that can induce long-lasting symptom relief. Similar rapid effects have been reported in rodents, but reports of lasting effects are limited. We sought to extend past findings by examining dose-response curves that overlap with the individual doses previously reported to induce lasting effects in rodents and determining whether effects...
Psychopharmacology May 21, 2011
Ketamine perturbs perception of the flow of time in healthy volunteers.
NMR in Biomedicine May 11, 2011
In vivo and ex vivo evidence for ketamine-induced hyperglutamatergic activity in the cerebral cortex of the rat: Potential relevance to schizophrenia.
Biological Psychiatry May 6, 2011 Amy K. Ricke, R. Snook, A. Anand 34 citations
Ms. M is a 42-year-old Caucasian married woman with a history of chronic left gluteal and left leg pain diagnosed as reflex sympathetic dystrophy. She was disabled by refractory symptoms that had failed a number of interventions and required high-dose opioids. Ms. M was otherwise high functioning and had completed a professional degree. The patient elected to undergo experimental IV ketamine...
The International Journal of Neuropsychopharmacology May 5, 2011 Retracted
A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department.
Journal of Medical Case Reports April 28, 2011 A. Elyassi, Robert Long, Robert P. Bejnarowicz et al.
IntroductionThe drugs gabapentin and ketamine are used frequently in the peri-operative setting. There is poor documentation whether or not gabapentin and ketamine interact to cause prolonged depression of the central nervous system.Case PresentationThe following is a case report in which a patient, a 58-year-old African-American man, with a history of post-traumatic stress disorder and chronic...
Molecular Psychiatry April 19, 2011
Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice.
Emerging health threats journal April 15, 2011 Sarbjeet S Kalsi, David M Wood, Paul I Dargan
Ketamine was originally synthesised for use as a dissociative anaesthetic, and it remains widely used legitimately for this indication. However, there is increasing evidence of non-medical recreational use of ketamine, particularly in individuals who frequent the night-time economy. The population-level and sub-population (clubbers) prevalence of recreational use of ketamine is not known but is...