Abstract Purpose of Review Psychedelic-assisted therapy (PAT) has re-emerged as a potential intervention for substance use disorders (SUDs), yet the psychological mechanisms underlying behaviour change remain poorly synthesised. This scoping review mapped and evaluated proposed psychological processes underpinning PAT in adults with SUDs. Recent Findings Peer-reviewed English-language empirical...
Veteran issues in the United States often figure prominently in policy debates and media coverage surrounding psychedelic substances, such as psilocybin mushrooms and ibogaine. This is partially driven by the need to improve access and efficacy of treatments for mental health conditions, especially conditions (such as posttraumatic stress disorder) that are more common among veterans than...
This is a preliminary, single-operator longitudinal observation report. Over a 19-day recording window spanning April 20 to May 8, 2026, one operator (the author) recorded 21 valid 250 Hz Muse Athena consumer EEG sessions across deep rest, sustained dialogue + running, multiplayer gaming, cannabinoid pharmacological states at four dose-duration profiles, prescription stimulant administration...
Psychedelic MedicineJuly 24, 2026Matthew C. Company, Dylan J. Lifshitz, M. Farris Sawaya et al.
This narrative review traces how the scientific understanding of psychedelics has intersected with “reward processing” from before the Controlled Substances Act (CSA) era to the present, emphasizing how cultural and regulatory climates shaped what was viewed as an acceptable research question. Reward processing is treated as a family of partially overlapping phenomena: (1) reward-linked...
For over five decades, there has been a significant quantitative discrepancy between the traditional knowledge of psychoactive plants of Old World and New World. While some 20th century scholars believed that it was motivated by cultural differences between the populations of the two regions of the globe, this consideration failed to take into account that the acquisition of awareness of the...
In recent years, psychedelics have shown promising results as therapeutic interventions for individuals with depression, terminal illnesses, substance use disorder, neurodegenerative diseases, trauma and obsessive-compulsive disorder. Moreover, research involving psychedelics have contributed to the understanding of the neurobiological mechanisms behind the "psychedelic state of consciousness"...
página 48|Revista de Psiquiatría del Uruguay|Volumen 90 Nº 1 Julio 2026| Psicodélicos en psiquiatría: un modelo multidimensional para el análisis...Resumo Nos últimos anos, o renovado interesse pelo uso medicinal dos psicodélicos adquiriu um caráter hipermidiatizado, estendendo sua presença de contextos clínicos e rituais tradicionais para cenários mais amplos, nos quais os objetivos...
With growing research on the use of psychedelics to treat mental health conditions, greater attention to the psychosocial procedures accompanying substance administration is warranted. This scoping review aims to categorize psychosocial protocols used in research involving psychedelics as psychiatric treatment according to their purpose, denomination, format, therapeutic orientation,...
Dominant psychedelic frameworks have been developed primarily from acute-phase neuroimaging and emphasize transient network reconfiguration during the drug state. Less attention has been given to the post-acute period, during which consequential electrophysiological and clinical changes may unfold. Ibogaine, whose human evidence is restricted to the post-acute window, provides a particularly...
PsychedelicsMay 30, 2026Vinicius Ryu Kami, Beatriz Borges Bueno Salle, Giovanni Porto et al.
Background Contemporary psychiatry is associated with several challenges, including limited remission rates in complex and severe psychiatric disorders. In this context, psychedelics have re-emerged globally as a promising therapeutic paradigm. Brazil occupies a unique position in this scenario, mainly due to the legal protection and cultural integration of Ayahuasca, which fosters a distinct...