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Depression: all studies

Page 976 of 1,034: studies 9,751 to 9,760 of 10,336, newest first. Back to the depression overview

Research

Subjective Theories about (Self‐)Treatment with Ayahuasca

Anthropology of Consciousness August 23, 2010 Janine Tatjana Schmid, Henrik Jungaberle, Rolf Verres 25 citations

ABSTRACT Ayahuasca is a psychoactive beverage that is mostly used in ritualized settings (Santo Daime rituals, neo‐shamanic rituals, and even do‐it‐yourself‐rituals). It is a common practice in the investigated socio‐cultural field to call these settings “healing rituals.” For this study, 15 people who underwent ayahuasca (self‐)therapy for a particular disease like chronic pain, cancer,...

DOI: 10.1111/j.1556-3537.2010.01028.x (opens in new tab) Ayahuasca Psychotherapist Coping psychology Clinical psychology

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Science August 19, 2010 Nanxin Li, Boyoung Lee, Rongjian Liu et al. 2,875 citations

The rapid antidepressant response after ketamine administration in treatment-resistant depressed patients suggests a possible new approach for treating mood disorders compared to the weeks or months required for standard medications. However, the mechanisms underlying this action of ketamine [a glutamate N-methyl-D-aspartic acid (NMDA) receptor antagonist] have not been identified. We observed...

DOI: 10.1126/science.1190287 (opens in new tab) Full text (opens in new tab) Ketamine Antidepressant Prefrontal cortex Pi3k/akt/mtor pathway +7

Taming the Ketamine Tiger

Anesthesiology August 6, 2010 Edward F. Domino, David S. Warner 517 citations

Pharmacologic actions of CI-581, a chemical derivative of phencyclidine, were determined in 20 volunteers from a prison population. The results indicate that this drug is an effective analgesic and anesthetic agent in doses of 1.0 to 2.0 mg per kilogram. With intravenous administration the onset of action is within 1 min and the effects last for about 5 to 10 min, depending on dosage level and...

What is the evidence for the use of mindfulness-based interventions in cancer care? A review.

Psycho-Oncology August 4, 2010 Christina Shennan, Sheila Payne, Deborah Fenlon

Objective: The aim of this paper is to present and critically appraise the evidence for the use of mindfulness-based interventions in cancer care. Methods: Systematic review methods were used. A thorough search of relevant major and specialised electronic databases was made and unpublished and ongoing work was also identified. Both qualitative and quantitative studies were eligible for...

DOI: 10.1002/pon.1819 (opens in new tab) Full text (opens in new tab) Humans Neoplasms Evidence-based medicine Medical oncology +2

Weathering storms: a cohort study of how participation in a mindfulness-based stress reduction program benefits women after breast cancer treatment.

Current Oncology August 2010 R H Matousek, P L Dobkin

A growing number of psychosocial interventions are being offered to cancer patients during and after their medical treatment. Here, we examined whether Mindfulness-Based Stress Reduction (MBSR), a stress management course, helps women to cope better with stress and illness once their breast cancer treatment is completed. Our aim was to understand how MBSR may benefit those who participate in...

Effects of Brief and Sham Mindfulness Meditation on Mood and Cardiovascular Variables

The Journal of Alternative and Complementary Medicine July 28, 2010 Fadel Zeidan, Susan K. Johnson, Nakia S Gordon et al. 323 citations

OBJECTIVES: Although long-term meditation has been found to reduce negative mood and cardiovascular variables, the effects of a brief mindfulness meditation intervention when compared to a sham mindfulness meditation intervention are relatively unknown. This experiment examined whether a 3-day (1-hour total) mindfulness or sham mindfulness meditation intervention would improve mood and...

Preparation of neoclerodane diterpenes as probes for the opioid receptor system

July 1, 2010 Anthony Lozama, Thomas E Prisinzano, David F. Wiemer et al. 1 citation

While there are a variety of therapeutics that interact with the opioid receptor system, they are not without side effects; including constipation, dysphoria and respiratory depression. A better understanding of the opioid receptor system may yield therapeutic agents with a limited side effect profile. The neoclerodane diterpene, salvinorin A, appears to interact at opioid receptors through a...

Embodied Integration Reflections on Mindfulness Based Cognitive Therapy (MBCT) and a Case For Mindfulness

Existential Analysis: Journal of the Society for Existential Analysis July 1, 2010 Jyoti Nanda

In an earlier paper (Nanda, 2009), I put forth the argument that the practice of mindfulness gives rise to existential-phenomenological themes and that both practices of Mindfulness and Existential therapy have many parallels. This paper explores how existential-phenomenological themes inevitably arise in Mindfulness Based Cognitive Therapy (MBCT), one of the models of 'third wave CBT' when it...

Afferent-specific AMPA receptor subunit composition and regulation of synaptic plasticity in midbrain dopamine neurons by abused drugs.

Journal of Neuroscience June 9, 2010 Cameron H Good, Carl R. Lupica

Ventral tegmental area (VTA) dopamine (DA) neurons play a pivotal role in processing reward-related information and are involved in drug addiction and mental illness in humans. Information is conveyed to the VTA in large part by glutamatergic afferents that arise in various brain nuclei, including the pedunculopontine nucleus (PPN). Using a unique rat brain slice preparation, we found that PPN...