medRxiv
November 1, 2022
Natasha L. Mason, Attila Szabo, Kim P. C. Kuypers et al.
6 citations
preprint
Abstract Patients characterized by stress-related disorders such as depression display elevated circulating concentrations of pro-inflammatory cytokines and a hyperactive HPA axis. Psychedelics are demonstrating promising results in treatment of such disorders, however the mechanisms of their therapeutic effects are still unknown. To date the evidence of acute and persisting effects of...
European Neuropsychopharmacology
November 1, 2022
Marco Solmi, Chaomei Chen, Charles Dauré et al.
55 citations
A scientometric analysis was realized to outline clinical research on psychedelics over the last century. Web of Science Core Collection was searched up to March 18, 2022, for publications on psychedelics. Network analyses and bibliometrics were combined, to identify research themes and trends with Bibliometrix and CiteSpace. The primary aim was to measure research trends evolution over time,...
Psychiatria Polska
October 31, 2022
Gniewko Więckiewicz, Dariusz Danel, Magdalena Piegza et al.
2 citations
MDMA is one of the most commonly used drugs in the world. Clinical studies are currently being conducted around the world on the use of this substance in the treatment of PTSD and alcoholism. However, little demographic information is available on users who use the substance for recreational purposes. The aim was to determine basic demographic and helath characteristics with validated tools....
Journal of Psychopharmacology
October 31, 2022
Grant Jones
28 citations
Background: Psychedelics are receiving renewed attention within Western medicine as they represent potential treatments for many difficult-to-treat mental health disorders. However, psychedelic science is limited in its focus and inclusion of racial and ethnic minorities. Hence, this study examines whether race and ethnicity moderate the associations that naturalistic...
Journal of clinical psychology in medical settings
October 30, 2022
Abbas Masjedi-Arani, Sedighe Hosseini, Shahab Lotfinia et al.
Some emotional and social aspects of infertility affect the response of the infertile women to the treatment. The purpose of this study was to compare the efficacy of unified transdiagnostic protocol (UP) and mindfulness-based stress reduction protocol (MBSR) on emotion regulation and uncertainty intolerance in infertile women receiving IVF. Forty-five infertile women with symptoms of anxiety...
European Archives of Psychiatry and Clinical Neuroscience
October 28, 2022
Golo Kronenberg, Annette Müller, Erich Seifritz et al.
Two recent randomized, placebo-controlled, double-blind trials have provided exciting new evidence for the rapid antidepressant effects of inhalational nitrous oxide [1, 2]. Intriguingly, nitrous oxide has been shown to faithfully mimic, in experimental rodents, key characteristics of drugs that block N-methyl-d-aspartate (NMDA) glutamate receptors such as, most notably, ketamine [3], the first...
October 28, 2022
Natalie Gukasyan, Roland R. Griffiths, David B. Yaden et al.
1 citation
preprint
Background: Psilocybin is being studied for depression, but little is known about how it interacts with common antidepressants. Limited data suggests that psilocybin’s effects may be diminished by serotonergic antidepressants acutely and even after a medication washout period.Aims: To learn the extent to which serotonergic antidepressants may diminish psilocybin’s effects both concurrently and...
CNS Drugs
October 27, 2022
S. Keam
An oral, fixed-dose combination of dextromethorphan hydrobromide [an uncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist and sigma-1 receptor agonist] and the antidepressant bupropion hydrochloride (an aminoketone and CYP2D6 inhibitor that increases dextromethorphan bioavailability) [AUVELITYTM; dextromethorphan/bupropion], is being developed by Axsome Therapeutics, Inc. for the...
October 26, 2022
George Danias, Jacob Appel
BACKGROUND Psychedelic substances have demonstrated promise in the treatment of depression, anxiety, and substance use disorders. Significant media coverage has been dedicated to psychedelic medicine, but it is unclear whether the public associates psilocybin with its potential therapeutic benefits. The COVID-19 pandemic led to an increase in depression, anxiety, and substance abuse in the...
Frontiers in Psychology
October 25, 2022
Yun-Chen Chang, Chang‐Fang Chiu, Chih-Kai Wang et al.
38 citations
Background and aim During the COVID-19 pandemic, an Internet-Mindfulness-Based Stress Reduction (iMBSR) program was delivered and may be better than an in-person approach. Our study evaluated the effects of iMBSR intervention on mental health, self-efficacy, and body image in women with breast cancer in Taiwan. Materials and methods Sixty-seven women with breast cancer were allocated to a...