Abstract Psychedelics (e.g., 3,4-Methylenedioxymethamphetamine [MDMA], lysergic acid diethylamide [LSD], psilocybin) are molecules that have the potential to produce rapid therapeutic effects when paired with psychotherapy. Randomized clinical trials of psychedelic-assisted psychotherapy (PAT) have shown promising results for post-traumatic stress disorder (PTSD), depression, and substance use...
Revista NeurociênciasOctober 16, 2024Vitória Pereira de Menezes, Luis Felipe Batista, Vicente Meneguzzo et al.
Introdução. Os transtornos mentais apresentam alta incidência na população, mas as opções terapêuticas são limitadas por efeitos colaterais e baixa eficácia. Nesse cenário, a Ayahuasca, utilizada por povos indígenas há milênios, surge como alternativa para tratar condições como ansiedade e depressão. Objetivo. Avaliar as mudanças psicológicas em participantes iniciantes de cerimônias com...
(1) Background: Lesbian, gay, bisexual, transgender, queer and other gender and sexual minority-identified (LGBTQ+) adolescents face mental and physical health disparities compared to their heterosexual and cisgender counterparts. Mindfulness-based interventions (MBIs) may be a potential method to intervene upon health disparities in this population. This pilot study explores the initial...
Abstract Background: Personality disorders (PDs) are characterized by impairments in psychological functioning for which pharmacologic treatments have demonstrated limited efficacy. Psychedelics may offer a possible PD treatment, given preliminary evidence for their potential long-term positive effects on psychological functioning. However, little is known about safety or potential therapeutic...
Psilocybin, a naturally occurring psychedelic compound, has recently emerged as a promising therapeutic agent for mental health. This Patent Highlight explores the innovative approaches to harnessing psilocybin's potential across various contexts. These include clinical trials targeting severe psychiatric conditions, the integration of low-dose psilocybin into dietary products to promote...
Background ‘Inhalants’ have been associated with poorer mental health in adolescence, but little is known of associations with specific types of inhalants. Aims We aimed to investigate associations of using volatile substances, nitrous oxide and alkyl nitrates with mental health problems in adolescence. Method We conducted a cross-sectional analysis using data from 13- to 14-year-old...
Over the last few years, the importance of Mindfulness in the field of research has grown exponentially, as it has demonstrated various benefits in improving mental health, although there are still various difficulties in putting these techniques into practice among the university population. However, Virtual Reality is emerging as a tool to improve the implementation of these techniques. For...
This paper presents a novel experiment investigating the relationship between virtual disembodiment and time perception in Virtual Reality (VR). Recent work demonstrated that the absence of a virtual body in a VR application changes the perception of time. However, the effects of simulating an out-of-body experience (OBE) in VR on time perception are still unclear. We designed an experiment...
Ketamine is an anesthetic that has been identified as an effective therapy for depressive disorders and related symptoms. Some studies have identified ketamine as having the potential to reduce substance use among individuals with a substance use disorder (SUD)-alongside psychotherapy. Further, SUDs often co-occur with depressive disorders. Using the National Mental Health Services Survey 2020,...
Psilocybin-assisted psychotherapy (PAP) has shown promise in treating mood and anxiety disorders in patients with cancer. However, patients with cancer often suffer from more than just depression and anxiety, and so far, PAP's effect on other psychiatric symptoms remains largely unknown. To address this gap, we pooled previously unpublished data from two phase II, randomized, placebo-controlled...